Search results for BCL2 associated agonist of cell death

Bcl2-Associated Agonist of Cell Death Phospho-Thr137 (BAD pT137) Antibody, Abbexa, abx032126
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq].
Host
Rabbit
Reactivity
Human
Applications
ELISA, DB
Conjugation
Unconjugated

Bcl2-Associated Agonist of Cell Death Phospho-Ser112 (BAD pS112) Antibody, Abbexa, abx032120
BAD promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Host
Rabbit
Reactivity
Mouse
Applications
ELISA, DB
Conjugation
Unconjugated

Bcl2-Associated Agonist of Cell Death Phospho-Ser91 (BAD pS91) Antibody, Abbexa, abx032125
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq].
Host
Rabbit
Reactivity
Human
Applications
ELISA, DB
Conjugation
Unconjugated

Bcl2-Associated Agonist of Cell Death Phospho-Ser111 (BAD pS111) Antibody, Abbexa, abx032119
BAD promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Host
Rabbit
Reactivity
Mouse
Applications
ELISA, DB
Conjugation
Unconjugated

Bcl2-Associated Agonist of Cell Death Phospho-Ser74 (BAD pS74) Antibody, Abbexa, abx032124
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq].
Host
Rabbit
Reactivity
Human
Applications
ELISA, DB
Conjugation
Unconjugated

BCL2 Associated Agonist Of Cell Death Phospho-Ser134 (BAD pS134) Antibody, Abbexa, abx329565
BAD (pS134) Antibody is a Rabbit Polyclonal against BAD (pS134).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated

Bcl2-Associated Agonist of Cell Death Phospho-Thr80 (BAD pT80) Antibody, Abbexa, abx032138
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq].
Host
Rabbit
Reactivity
Human
Applications
ELISA, DB
Conjugation
Unconjugated

Bcl2-Associated Agonist of Cell Death Phospho-Tyr76 (BAD pY76) Antibody, Abbexa, abx032128
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq].
Host
Rabbit
Reactivity
Human
Applications
ELISA, DB
Conjugation
Unconjugated

Bcl2-Associated Agonist of Cell Death Phospho-Tyr110 (BAD pY110) Antibody, Abbexa, abx032127
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq].
Host
Rabbit
Reactivity
Human
Applications
ELISA, DB
Conjugation
Unconjugated

Bcl2-Associated Agonist of Cell Death Phospho-Ser32 (BAD pS32) Antibody, Abbexa, abx032136
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq].
Host
Rabbit
Reactivity
Human
Applications
ELISA, DB
Conjugation
Unconjugated
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