Search results for Braf antibody
Serine/threonine-Protein Kinase B-Raf (BRAF) Antibody, Abbexa, abx302175
BRAF Antibody is a Rabbit Polyclonal against BRAF.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
Serine/threonine-Protein Kinase B-Raf (BRAF) Antibody, Abbexa, abx033697
BRAF, a member of the RAF subfamily of Ser/Thr protein kinases, is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. This cytoplasmic protein is expressed in brain and testis. Defects in BRAF are involved in a wide range of cancers including lung cancer and non-Hodgkin lymphoma (NHL). This protein contains 1 zinc-dependent phorbol-ester and DAG binding domain.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Serine/Threonine-Protein Kinase B-Raf (BRAF) Antibody, Abbexa, abx227130
Serine/Threonine-Protein Kinase B-Raf (BRAF) Antibody is a Rabbit Monoclonal antibody for the detection of B-raf.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC
Conjugation
Unconjugated
Serine/threonine-protein kinase B-raf (BRAF) Antibody, Abbexa, abx402052
Serine/threonine-protein kinase B-raf (BRAF) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human BRAF.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Serine/threonine-Protein Kinase B-Raf (BRAF) Antibody, Abbexa, abx010442
B-Raf is a tyrosine kinase-like kinase of the RAF family. Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Frequently mutated in thyroid cancers, skin melanomas and at lower frequency in a wide range of human cancers. An activating mutation, mimicking phosphorylation of the activation loop, is seen in 60% of malignant melanoma samples. Raf mutations are generally exclusive to Ras activating mutations. Activating mutations are also seen in ~10% of colorectal cancers, in lung cancers and gliomas, and at a lower rate in several other tumors. Inactivating mutations are also seen and may result in activation of c-Raf and Erk. Mutations in B-Raf, MEK1 and MEK2 also associated with cardiofaciocutaneous syndrome, displaying morphological, cardiac and mental defects. Approved Inhibitor: Nexavar/Sorafenib.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Serine/threonine-Protein Kinase B-Raf (BRAF) Antibody, Abbexa, abx015780
BRAF: v-raf murine sarcoma viral oncogene homolog B1, also known as BRAF1; RAFB1; B-RAF1; FLJ95109.Entrez Protein NP_004324.It is the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway.B-Raf contains three consensus Akt phosphorylationsites (Ser364, Ser428, and Thr439).B-Raf is a key regulatory molecule of the mitogen-activated protein kinase kinase (MEK), it has a long amino-terminal region,the region is essential for homo-dimerization of B-Raf and hetero-dimerization of B-Raf and c-Raf at the plasma membrane, followed by phosphorylation of Thr118 in the amino-terminal B-Raf-specific region.Notably, in calcium ionophore-stimulated HeLa cells, B-Raf could propagate signals to MEK under the basal level of GTP-Ras.Expression of Raf-B is highly restricted with highestlevels in the cerebrum and testes and defects in braf are involved in a wide range of cancers.The BRAF gene mutation is frequently detected in papillary thyroid carcinoma,melanocytic nevi, primary cutaneous melanomas and colorectal cancers.
Host
Mouse
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Serine/threonine-Protein Kinase B-Raf (BRAF) Antibody, Abbexa, abx230941
BRAF Antibody is a Rabbit Polyclonal against BRAF.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
![Alexa Fluor® 647 Anti-BRAF antibody [EP152Y] Brand Logo](https://file.buyantibody.com/public/brand/20260608/Abcam.jpg "Click to View Alexa Fluor® 647 Anti-BRAF antibody [EP152Y] Product Detail")
Alexa Fluor® 647 Anti-BRAF antibody [EP152Y], Abcam, AB309081
Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company. The Alexa Fluor® dye included in this product is provided under an intellectual property license from Life Technologies Corporation. As this product contains the Alexa Fluor® dye, the purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). As this product contains the Alexa Fluor® dye the sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: in manufacturing; (ii) to provide a service, information, or data in return for payment (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are sold for use in research. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or [email protected].
Host
Rabbit
Reactivity
Human, Human, Mouse, Rat
Applications
IHC-P
Conjugation
Alexa Fluor® 647
Serine/threonine-Protein Kinase B-Raf (BRAF) Antibody (HRP), Abbexa, abx314761
BRAF Antibody (HRP) is a Rabbit Polyclonal against BRAF conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Serine/threonine-Protein Kinase B-Raf (BRAF) Antibody (FITC), Abbexa, abx314762
BRAF Antibody (FITC) is a Rabbit Polyclonal against BRAF conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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