Search results for FOXO1 antibody
Forkhead Box Protein O1 (FOXO1) Antibody, Abbexa, abx329311
FOXO1 Antibody is a Rabbit Polyclonal against FOXO1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Forkhead Box Protein O1 (FOXO1) Antibody, Abbexa, abx010804
Forkhead Box Protein O1 (FOXO1) Antibody is a Rabbit Polyclonal antibody for the detection of FOXO1. Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Forkhead Box Protein O1 (FOXO1) Antibody, Abbexa, abx329179
FOXO1 Antibody is a Rabbit Polyclonal against FOXO1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Forkhead Box Protein O1 (FOXO1) Antibody, Abbexa, abx102441
Polyclonal Antibody to Forkhead Box Protein O1 (FOXO1).
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Forkhead Box Protein O1 (FOXO1) Antibody, Abbexa, abx455918
Forkhead Box Protein O1 (FOXO1) Antibody is a Rabbit polyclonal antibody for the detection of Human Forkhead Box Protein O1 (FOXO1).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Forkhead Box Protein O1 (FOXO1) Antibody, Abbexa, abx012777
Rabbit polyclonal antibody against FOXO1 protein. Immunogen region is N-terminal.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, IHC
Conjugation
Unconjugated
Forkhead Box Protein O1 (FOXO1) Antibody, Abbexa, abx102440
Polyclonal Antibody to Forkhead Box Protein O1 (FOXO1).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Forkhead Box Protein O1 (FOXO1) Antibody, Abbexa, abx011935
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
Host
Mouse
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Forkhead Box Protein O1 (FOXO1) Antibody, Abbexa, abx233201
FOXO1 Antibody is a Rabbit Polyclonal against FOXO1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Forkhead Box Protein O1 (FOXO1) Antibody, Abbexa, abx242215
FOXO1 Antibody is a Rabbit Polyclonal against FOXO1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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