Search results for SPHK1 antibody

SPHK1 antibody [C3], C-term, Genetex, GTX104724

Sphingosine Kinase 1 (SPHK1) Antibody, Abbexa, abx033251

Sphingosine Kinase (SphK) catalyzes the phosphorylation of the lipid sphingosine, creating the bioactive lipid sphingosine-1-phosphate (S1P). S1P subsequently signals through cell surface G protein-coupled receptors, as well as intracellularly, to modulate cell proliferation, survival, motility and differentiation. SphK is an important signaling enzyme which is activated by diverse agents, including growth factors that signal through receptor tyrosine kinases, agents activating G protein-coupled receptors, and immunoglobulin receptors. Two SphK isotypes, SphK-1 and SphK-2, have been cloned, and both isotypes are ubiquitously expressed. SphK-1 has been shown to mediate cell growth, prevention of apoptosis, and cellular transformation, and is upregulated in a variety of human tumors. In contrast, SphK-2 increases apoptosis, and may be responsible for phosphorylating and activating the immunosuppressive drug FTY720.

Anti-SPHK1 antibody [EPR24511-37], Abcam, AB302714

Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected] Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Sphingosine Kinase 1 (SPHK1) Antibody, Abbexa, abx238173

SPHK1 Antibody is a Rabbit Polyclonal against SPHK1.

Sphingosine Kinase 1 (SPHK1) Antibody, Abbexa, abx025123

SPHK1 is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.

Sphingosine Kinase 1 (SPHK1) Antibody, Abbexa, abx457279

Sphingosine Kinase 1 (SPHK1) Antibody is a Rabbit polyclonal antibody for the detection of Human Sphingosine Kinase 1 (SPHK1).

Sphingosine Kinase 1 (SPHK1) Antibody (Biotin), Abbexa, abx314349

SPHK1 Antibody (Biotin) is a Rabbit Polyclonal against SPHK1 conjugated to Biotin.

Sphingosine Kinase 1 (SPHK1) Antibody (HRP), Abbexa, abx314347

SPHK1 Antibody (HRP) is a Rabbit Polyclonal against SPHK1 conjugated to HRP.

Sphingosine Kinase 1 (SPHK1) Antibody (FITC), Abbexa, abx314348

SPHK1 Antibody (FITC) is a Rabbit Polyclonal against SPHK1 conjugated to FITC.

Purified anti-SPHK1 Antibody anti-SPHK1 - 1A5SC, BioLegend, 658302