Search results for Sonic hedgehog protein
Sonic Hedgehog Protein (SHH) Antibody, Abbexa, abx015984
This gene encodes a protein that is instrumental in patterning the early embryo.It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites.Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar.The protein is made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing.More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo.Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres.HPE is manifested by facial deformities.It is also thought that mutations in this gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities.Additionally, mutations in a long range enhancer located approximately 1 megabase upstream of this gene disrupt limb patterning and can result in preaxial polydactyly.
Host
Mouse
Reactivity
Human, Mouse, Monkey
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
Sonic Hedgehog Protein (SHH) Antibody, Abbexa, abx403722
Human Sonic Hedgehog Protein (SHH) Antibody is a Mouse monoclonal against Sonic Hedgehog Protein (SHH).
Host
Mouse
Reactivity
Human
Applications
IHC
Conjugation
Unconjugated
Sonic Hedgehog Protein A (SHHA) Antibody (FITC), Abbexa, abx319978
shha Antibody (FITC) is a Rabbit Polyclonal against shha conjugated to FITC.
Host
Rabbit
Reactivity
Zebrafish
Applications
Conjugation
FITC
Sonic Hedgehog Protein (SHH) Antibody (FITC), Abbexa, abx346245
Sonic Hedgehog Protein (SHH) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human SHH.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
Sonic Hedgehog Protein (SHH) Antibody (HRP), Abbexa, abx346244
Sonic Hedgehog Protein (SHH) Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP for the detection of Human SHH.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Sonic Hedgehog Protein (SHH) Antibody Pair, Abbexa, abx370329
Sonic Hedgehog Protein (SHH) Antibody Pair for use in Sandwich ELISA assay development. This antibody pair contains: Component 5 × 96 tests 10 × 96 tests Capture Antibody200 µg 400 µg Biotin-Conjugated Detection Antibody 50 µg 100 µg Standard 2 µg 10 µg Please note that quantities and concentrations may change between different batches. It is recommended to use this antibody pair with abx098958 Antibody Pair Support Kit (Sandwich Method).
Host
Reactivity
Rat
Applications
ELISA
Conjugation
Unconjugated
Sonic Hedgehog Protein A (SHHA) Antibody (HRP), Abbexa, abx319977
shha Antibody (HRP) is a Rabbit Polyclonal against shha conjugated to HRP.
Host
Rabbit
Reactivity
Zebrafish
Applications
ELISA
Conjugation
HRP
Sonic Hedgehog Protein (SHH) Antibody (Biotin), Abbexa, abx346246
Sonic Hedgehog Protein (SHH) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin for the detection of Human SHH.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Sonic Hedgehog Protein (SHH) Antibody (Biotin), Abbexa, abx273268
Sonic Hedgehog Protein (SHH) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Sonic Hedgehog Protein (SHH).
Host
Rabbit
Reactivity
Rat
Applications
WB, IHC, IF/ICC
Conjugation
Biotin
Sonic Hedgehog Protein A (SHHA) Antibody (Biotin), Abbexa, abx319979
shha Antibody (Biotin) is a Rabbit Polyclonal against shha conjugated to Biotin.
Host
Rabbit
Reactivity
Zebrafish
Applications
ELISA
Conjugation
Biotin
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