Search results for APC/Fire

APC/Fire 750 anti-human TIGIT VSTM3 Antibody anti-TIGIT - A15153G, BioLegend, 372708

This clone can suppress anti-CD3 induced T cell proliferationin vitrobased on in-house testing.This clone has been tested in-house and determined to not be suitable for applications in immunohistochemistry of paraffin-embedded tissue sections (IHC-P).Additional reported applications (for the relevant formats) include: Blocking1.

APC/Fire™ 750 anti-human Perforin Antibody Perforin, B-D48, BioLegend, 353317

APC/Fire™ 750 anti-human Perforin Antibody Perforin, B-D48, BioLegend, 353318

APC/Fire™ 810 anti-human CD56 (NCAM) Antibody, CD56, HCD56, BioLegend, 318355

Clone HCD56 is not recommended for immunohistochemistry formalin-fixed paraffin-embedded tissue.

APC/Fire™ 810 anti-human CD56 (NCAM) Antibody, CD56, HCD56, BioLegend, 318356

Clone HCD56 is not recommended for immunohistochemistry formalin-fixed paraffin-embedded tissue.

GMP APC/Fire™ 750 anti-human CD64 Antibody, CD64, 10.1, BioLegend, 260368

Clone 10.1 recognizes the EC3 epitope of CD64. While both contain the EC3 domain, in-house testing suggests that clone 10.1 preferentially binds to CD64A (FcγRIA), but not CD64B (FcγRIB). Additional reported applications (for the relevant formats) include: blocking of human IgG3 and murine IgG2a binding to FcγRI2,5,6,11and immunohistochemical staining of acetone-fixed frozen tissue sections12.

GMP APC/Fire™ 750 anti-human CD20 Antibody, CD20, 2H7, BioLegend, 260350

The epitope recognized by clone 2H7 has been mapped to the sequence YNCEPANPSEKNSPST which lies in the large extracellular loop of human CD20. Additional reported applications (for the relevant formats) include: immunoprecipitation4and immunohistochemical staining of acetone-fixed frozen sections5.

GMP APC/Fire™ 750 anti-human CD16 Antibody, CD16, 3G8, BioLegend, 260258

The 3G8 antibody clone blocks neutrophil phagocytosis and stimulates NK cell proliferation. It has been reported that this clone interacts with the FcγRIIa and FcγRIIIb receptors causing neutrophil activation and aggregation18.Due to this phenomenon staining in whole blood may cause a reduction in the number of granulocytes or alter their scatter profile.Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections6, immunoprecipitation3, stimulation of NK cell proliferation4, blocking of phagocytosis5, and blocking of immunoglobulin binding to FcγRIII7,8. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 302049, 302050, 302057, 302058).

GMP APC/Fire™ 750 anti-human CD21 Antibody, CD21, Bu32, BioLegend, 260460

Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections4.

GMP APC/Fire™ 750 anti-human CD71 Antibody, CD71, CY1G4, BioLegend, 260382