Search results for TP53
Mouse Cellular Tumor Antigen p53 (TP53) ELISA Kit, Abbexa, abx154821
Mouse Cellular Tumor Antigen p53 (TP53) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Cellular Tumor Antigen p53 (TP53) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Tumor Protein p53 (TP53)No significant cross-reactivity or interference between Tumor Protein p53 (TP53) and analogues was observed.
Host
Reactivity
Mouse
Applications
ELISA
Conjugation
Human TP53-target gene 5 protein (TP53TG5) ELISA Kit, Abbexa, abx548550
Human TP53-target gene 5 protein (TP53TG5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human TP53-target gene 5 protein (TP53TG5) concentrations in tissue homogenates, cell lysates and other biological fluids.
Host
Reactivity
Human
Applications
ELISA
Conjugation
Cellular Tumor Antigen p53 Phospho-Ser315 (TP53 pS315) Antibody, Abbexa, abx000509
TP53 (pS315) Antibody is a Rabbit Polyclonal antibody against TP53 (pS315). This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Mouse TP53-Regulated Inhibitor of Apoptosis 1 (TRIAP1) ELISA Kit, Abbexa, abx551302
Mouse TP53-Regulated Inhibitor of Apoptosis 1 (TRIAP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse TP53-Regulated Inhibitor of Apoptosis 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Host
Reactivity
Mouse
Applications
ELISA
Conjugation
Cellular Tumor Antigen p53 Acetyl-Lys320 (TP53 AcK320) Antibody, Abbexa, abx323602
Acetyl-TP53 (K320) Antibody is a Rabbit Polyclonal against Acetyl-TP53 (K320).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Cellular Tumor Antigen p53 Phospho-Ser378 (TP53 pS378) Antibody, Abbexa, abx327409
TP53 (pS378) Antibody is a Rabbit Polyclonal against TP53 (pS378).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Cellular Tumor Antigen p53 Phospho-Ser6 (TP53 pS6) Antibody, Abbexa, abx000209
TP53 (pS6) Antibody is a Rabbit Polyclonal antibody against TP53 (pS6). This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Cellular Tumor Antigen p53 Phospho-Ser9 (TP53 pS9) Antibody, Abbexa, abx243041
TP53 (pS9) Antibody is a Monoclonal Antibody against TP53.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IF/ICC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 Acetyl-Lys382 (TP53 AcK382) Antibody, Abbexa, abx159303
Acetyl-TP53 (K382) Antibody is a Mouse Monoclonal against Acetyl-TP53 (K382).
Host
Mouse
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 Phospho-Ser20 (TP53 pS20) Antibody, Abbexa, abx031895
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of the TP53 gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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