Search results for 12

Anti-Synaptotagmin-12 Antibody (N277/7), AntibodySystem, RHN11702

C1-INH, Human, clone 15/12, Hycult Biotech, HM2411

Mouse monoclonal antibody HM2411 recognizes human C1-inhibitor. The complement system plays important roles in both innate and adaptive immune response and can produce an inflammatory and protective reaction to challenges from pathogens before an adaptive response can occur. There are three pathways of complement activation. The classical pathway (CP) is initiated by Immune complexes; the lectin pathway (LP) by surface bound mannan binding lectin; and the alternative (AP) by all the surfaces that are not specifically protected against it. Each generates a C3 convertase, a serine protease that cleaves the central complement protein C3, and generates the major cleavage fragment C3b. The C3 and C5 convertases are enzymatic complexes that initiate and amplify the activity of the complement pathways and ultimately generate the cytolytic MAC (C5b-9). C1 inhibitor (C1-INH) is a heavily glycosylated single chain molecule of 500 AA. It inhibits multiple enzymes, including C1s&r of the CP and MASP-1&2 of the LP, plasmin in the fibrinolytic system and Factor XIIa&XIa of the contact and coagulation system. C1-INH is also called C1 esterase inhibitor, due C1s is often cleaved by synthetic esters in spectrophotometry. C1-INH plays an important role in suppression of inflammation and vascular permeability. C1-INH binding of C1 to the catalytic site of both C1r and C1s releases the latter two from the complex. As a result the activation of the complement system is blocked. Binding to MASP blocks function and thereby consumption of C2,3&4. C1-INH spares the AP, leaving part of the innate antibacterial defense intact. Besides, C1-INH can directly bind and neutralize LPS, inhibiting sepsis and endotoxin shock. C1-INH administration is the common treatment for hereditary angioedema (HAE). A disease commonly caused by heterozygous deficiency of C1-INH and leading to low levels of functional C1-INH and recurrent episodes of dermal and submucosal swelling. This is mediated by its ability to control activation of the contact system in inhibiting bradykinin generation and thereby control of vascular permeability.

Human Septin-12 (SEPT12) ELISA Kit, Abbkine, KTE60828

• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.

Human Mucin-12 (MUC12) ELISA Kit, Abbkine, KTE61464

• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.

Mouse Synaptotagmin-12 (SYT12) ELISA Kit, Abbkine, KTE70297

• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.

Human Synaptotagmin-12 (SYT12) ELISA Kit, Abbkine, KTE60427

• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.

Human Syntaxin-12 (STX12) ELISA Kit, Abbexa, abx259865

Human Syntaxin-12 (STX12) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Syntaxin-12 (STX12) concentrations in tissue homogenates, cell lysates and other biological fluids.

Rat Keratin 12 (KRT12) ELISA Kit, Abbexa, abx529186

Rat Keratin 12 (KRT12) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Keratin, type I cytoskeletal 12 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

Mouse Aquaporin 12 (AQP12) ELISA Kit, Abbexa, abx517720

Mouse Aquaporin 12 (AQP12) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Aquaporin 12 (AQP12) concentrations in tissue homogenates, cell lysates and other biological fluids.

Glucose Transporter 12 / GLUT12 (SLC2A12) Antibody, Abbexa, abx339697

SLC2A12 Antibody is a Rabbit Polyclonal against SLC2A12.