Search results for Factor A

Factor H, Mouse, mAb 1A2, Hycult Biotech, HM1119
Monoclonal antibody 1A2 recognizes mouse complement factor H (CFH). CFH is the first regulatory protein of the alternative pathway of the complement system. There are three pathways of complement activation; classical, alternative, and lectin activation pathway. These pathways converge to form C3/C5 convertases that generate C3a, C3b,C5a, and C5b, each with substantial biologic activity. Complement regulators are necessary to prevent the injudicious production of these mediators and potential injury to self-tissue. The plasma proteins CFH, C4-binding protein and the cell membrane proteins complement receptor 1 (CR1; CD35), decay-accelerating factor (CD55), and membrane co-factor protein (CD46) all are members of the regulators of complement activation family. These proteins have natural affinity for C3b and/or C4b, which confers on them the ability to accelerate the intrinsic decay of C3/C5 convertases and/or act as co-factor for the cleavage and inactivation (i) of C3b and C4b by complement factor I (CFI). Genetic human analyses reveals a clear association of CFH with different human diseases. These include diseases of the kidney, the atypical form of Hemolytic Uremic Syndrome (aHUS) and membranoproliferative glomerulonephritis (MPGN). Furthermore, CFH is associated with age-related macular degeneration (AMD), a disease of the eye.
Host
Mouse
Reactivity
Applications
Conjugation

Transcription Factor 12 (TCF12) Antibody, Abbexa, abx321364
TCF12 Antibody is a Rabbit Polyclonal against TCF12.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IP
Conjugation
Unconjugated

Transcription Factor 4 (TCF4) Antibody, Abbexa, abx149368
Transcription Factor 4 (TCF4) Antibody is a Rabbit Polyclonal antibody for the detection of TCF4. Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB
Conjugation
Unconjugated

Coagulation Factor XI (F11) Antibody, Abbexa, abx101989
Polyclonal Antibody to Coagulation Factor XI (F11).
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated

Nerve Growth Factor (NGF) Antibody, Abbexa, abx217163
NGF Antibody is a Rabbit Polyclonal against NGF.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Conjugation

Trefoil Factor 2 (TFF2) Antibody, Abbexa, abx224119
TFF2 Antibody is a Mouse Monoclonal against TFF2.
Host
Mouse
Reactivity
Human
Applications
ELISA, FCM
Conjugation

Ciliary Neurotrophic Factor (CNTF) Antibody, Abbexa, abx171751
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Ciliary Neurotrophic Factor (CNTF) Antibody is a Mouse Monoclonal antibody against Ciliary Neurotrophic Factor (CNTF).
Host
Mouse
Reactivity
Rabbit
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated

transcription termination factor-Specific Antibody, Abbexa, abx238928
transcription termination factor-Specific Antibody is a Mouse Monoclonal against transcription termination factor-Specific.
Host
Mouse
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated

Von Willebrand Factor (VWF) Antibody, Abbexa, abx461872
Von Willebrand Factor (VWF) Antibody is a monoclonal Nanobody for the detection of Human VWF.
Host
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated

Coagulation Factor VII (F7) Antibody, Abbexa, abx131879
Coagulation Factor VII Antibody is a Mouse Monoclonal against Coagulation Factor VII.
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
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