Search results for RAC
RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody, Abbexa, abx010368
Akt2 (also designated protein kinase B beta or v-akt murine thymoma viral oncogene homolog 2), with 481-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt3. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. Among the members of AKT family, Akt2 is associated with the development of human cancers. Akt2 inhibits cisplatin-induced JNK/p38 and Bax activation through phosphorylation of ASK1 and thus, plays an important role in chemoresistance. Further, Akt2 plays a specific role in muscle differentiation.
Host
Mouse
Reactivity
Human, Rat, Monkey
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
RAC-Alpha Serine/threonine-Protein Kinase (Akt) Antibody, Abbexa, abx249426
Akt (Ab-450) Antibody is a Rabbit Polyclonal against Akt.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
RAC-Alpha Serine/threonine-Protein Kinase (AKT1) Antibody, Abbexa, abx224402
AKT1 Antibody is a Mouse Monoclonal against AKT1.
Host
Mouse
Reactivity
Human, Monkey, Rat
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
RAC-Alpha Serine/threonine-Protein Kinase (AKT1) Antibody, Abbexa, abx011913
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene./AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins./The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described.
Host
Mouse
Reactivity
Human, Mouse, Monkey
Applications
ELISA, WB
Conjugation
Unconjugated
RAC-Alpha Serine/threonine-Protein Kinase (AKT1) Antibody, Abbexa, abx230271
AKT1 Antibody is a Mouse Monoclonal against AKT1.
Host
Mouse
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC, IP
Conjugation
Unconjugated
RAC-Alpha Serine/threonine-Protein Kinase (AKT1) Antibody, Abbexa, abx004230
AKT1 Antibody is a Rabbit Polyclonal antibody against AKT1. The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
RAC-Alpha Serine/Threonine-Protein Kinase (AKT1) Antibody, Abbexa, abx455146
RAC-Alpha Serine/Threonine-Protein Kinase (AKT1) Antibody is a Rabbit polyclonal antibody for the detection of Human RAC-Alpha Serine/Threonine-Protein Kinase (AKT1).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
RAC-Gamma Serine/threonine-Protein Kinase (AKT3) Antibody, Abbexa, abx224430
AKT3 Antibody is a Mouse Monoclonal against AKT3.
Host
Mouse
Reactivity
Human
Applications
ELISA, FCM
Conjugation
Unconjugated
RAC-Alpha Serine/Threonine-Protein Kinase (AKT1) Antibody, Abbexa, abx326605
AKT1 Antibody is a Rabbit Polyclonal against AKT1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
RAC-Alpha Serine/Threonine-Protein Kinase (AKT1) Antibody, Abbexa, abx330043
AKT1 Antibody is a Rabbit Polyclonal against AKT1.
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
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