Search results for AKT1
RAC-Alpha Serine/threonine-Protein Kinase Phospho-Ser473 (AKT1 pS473) Antibody, Abbexa, abx031983
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, DB
Conjugation
Unconjugated
RAC-Alpha Serine/Threonine-Protein Kinase Phospho-Ser473 (AKT1 pS473) Antibody, Abbexa, abx012415
Rabbit polyclonal antibody against Akt protein. Immunogen region is C-terminal. Specificity is as follows for the reactive species: H:S473, M:S473, R:S473.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
RAC-Alpha Serine/threonine-Protein Kinase Phospho-Ser129 (AKT1 pS129) Antibody, Abbexa, abx031825
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.
Host
Rabbit
Reactivity
Human
Applications
ELISA, DB
Conjugation
Unconjugated
RAC-Alpha Serine/threonine-Protein Kinase Phospho-Thr450 (AKT1 pT450) Antibody, Abbexa, abx032108
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].
Host
Rabbit
Reactivity
Human
Applications
ELISA, DB
Conjugation
Unconjugated
RAC-Alpha Serine/threonine-Protein Kinase Phospho-Thr308 (AKT1 pT308) Antibody, Abbexa, abx032098
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/Teonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].
Host
Rabbit
Reactivity
Human
Applications
ELISA, IF/ICC, DB
Conjugation
Unconjugated
RAC-Alpha Serine/threonine-Protein Kinase Phospho-Thr308 (AKT1 pT308) Antibody, Abbexa, abx000352
AKT1 (pT308) Antibody is a Rabbit Polyclonal antibody against AKT1 (pT308). The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
RAC-Alpha Serine/threonine-Protein Kinase Phospho-Ser473 (AKT1 pS473) Antibody, Abbexa, abx236402
AKT1 pS473 Antibody is a Mouse Monoclonal against AKT1 pS473.
Host
Mouse
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
RAC-Alpha Serine/Threonine-Protein Kinase Phospho-Ser473 (AKT1 pS473) Antibody, Abbexa, abx227061
RAC-Alpha Serine/Threonine-Protein Kinase Phospho-Ser473 (AKT1 pS473) Antibody is a Rabbit Monoclonal antibody for the detection of AKT1 (pSer-473).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IF/ICC, IP
Conjugation
Unconjugated
RAC-Alpha Serine/Threonine-Protein Kinase Phospho-Thr308 (AKT1 pT308) Antibody, Abbexa, abx012718
Rabbit polyclonal antibody against AKT1 protein. Immunogen region is Internal. Specificity is as follows for the reactive species: H:T308, M:T308, R:T308.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
RAC-Alpha Serine/threonine-Protein Kinase Phospho-Ser129 (AKT1 pS129) Antibody, Abbexa, abx333414
AKT1 (pS129) Antibody is a Rabbit Polyclonal against AKT1 (pS129).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
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