Search results for AMPK
5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 (AMPK alpha 2) Antibody, Abbexa, abx033381
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 (AMPK alpha 2) Antibody, Abbexa, abx033228
AMPK2 alpha2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
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PathScan®Phospho-AMPK alpha (Thr172) Sandwich ELISA Antibody Pair#7955, Cell Signaling Technology (CST), 7955
For Antibody Pair specificity and sensitivity, please refer to the corresponding PathScan®Sandwich ELISA Kit. Note: This antibody pair detects proteins from the indicated species, as determined through in-house testing, but may also detect homologous proteins from other species.
Host
Reactivity
Human, Mouse
Applications
Conjugation
Phospho-AMPK Substrate Motif [LXRXX(pS/pT) MultiMab®Rabbit Monoclonal Antibody mix#5759, Cell Signaling Technology (CST), 5759
Phospho-AMPK Substrate Motif [LXRXX(pS/pT) MultiMab®Rabbit Monoclonal Antibody mix preferentially recognizes endogenous proteins and peptides bearing the LXRXXpS/pT motif. This antibody also cross-reacts with proteins and peptides that only harbor an RXXpS/pT motif.
Host
Reactivity
All Species Expected
Applications
Western Blotting: 1:1000 Immunoprecipitation: 1:100 Peptide ELISA (DELFIA): 1:1000
Conjugation
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