Search results for P53

Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx403201

Human Cellular Tumor Antigen p53 (TP53) Antibody is a Mouse monoclonal against Cellular Tumor Antigen p53 (TP53).

P53 Upregulated Modulator of Apoptosis (PUMA) Antibody, Abbexa, abx104029

Polyclonal Antibody to p53 Upregulated Modulator Of Apoptosis (PUMA).

Anti-Mouse TP53/p53 Polyclonal Antibody, AntibodySystem, PMC10001

Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx323524

TP53 Antibody is a Rabbit Polyclonal against TP53.

Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx000648

TP53 Antibody is a Rabbit Polyclonal antibody against TP53. This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).

Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx328280

TP53 Antibody is a Rabbit Polyclonal against TP53.

Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx403199

Human Cellular Tumor Antigen p53 (TP53) Antibody is a Mouse monoclonal against Cellular Tumor Antigen p53 (TP53).

Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx037925

Rabbit Polyclonal against the p53 protein.

Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx032760

Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of the TP53 gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome.

Phospho-p53-S46 Rabbit pAb- ABclonal, ABclonal, AP0476