Search results for homolog
Denticleless Protein Homolog (DTL) Antibody, Abbexa, abx026016
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX (DTL) complex, also named CRL4 (CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21 (CIP1). CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21 (CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing. Most substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX (DTL) complex, leading to their degradation. In undamaged proliferating cells, the DCX (DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, FCM
Conjugation
Unconjugated
Frizzled Homolog 4 (FZD4) Antibody, Abbexa, abx432058
Frizzled 4 Antibody is a Goat Polyclonal antibody against Frizzled 4.
Host
Goat
Reactivity
Human
Applications
P-ELISA, WB
Conjugation
Unconjugated
Slit Homolog 1 (Slit1) Antibody, Abbexa, abx101375
Polyclonal Antibody to Slit Homolog 1 (Slit1).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Peroxidasin Homolog (PXDN) Antibody (Biotin), Abbexa, abx274667
Peroxidasin Homolog (PXDN) Antibody (Biotin) is a Rabbit Polyclonal antibody (abx101906) conjugated to Biotin against Peroxidasin Homolog (PXDN).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Biotin
Slit Homolog 2 (SLIT2) Antibody, Abbexa, abx404636
Human Slit Homolog 2 (SLIT2) Antibody is a Rabbit polyclonal against Slit Homolog 2 (SLIT2).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Mindbomb Homolog 1 (MIB1) Antibody, Abbexa, abx101780
Polyclonal Antibody to Mindbomb Homolog 1 (MIB1).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Brother of CDO Homolog (BOC) Antibody, Abbexa, abx376036
Brother of CDO Homolog (BOC) Antibody is a Rabbit Polyclonal antibody against Brother of CDO Homolog (BOC).
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Dispatched Homolog 1 (DISP1) Antibody, Abbexa, abx112105
Dispatched Homolog 1 (Drosophila) Antibody is a Rabbit Polyclonal antibody against Dispatched Homolog 1 (Drosophila).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Frizzled Homolog 1 (FZD1) Antibody, Abbexa, abx101751
Polyclonal Antibody to Frizzled Homolog 1 (FZD1).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Frizzled Homolog 10 (FZD10) Antibody, Abbexa, abx102020
Polyclonal Antibody to Frizzled Homolog 10 (FZD10).
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
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