Search results for CD59 glycoprotein
CD59 Glycoprotein (CD59) Antibody, Abbexa, abx011952
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC, IF/ICC, FCM
Conjugation
Unconjugated
CD59 Glycoprotein (CD59) Antibody, Abbexa, abx036096
Rabbit Polyclonal against the CD59 protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
CD59 Glycoprotein (CD59) Antibody (FITC), Abbexa, abx139311
CD59 Antibody is a Mouse Monoclonal against CD59.
Host
Mouse
Reactivity
Human
Applications
FCM
Conjugation
FITC
CD59 Glycoprotein, Rat, mAb TH9, Hycult Biotech, HM3037
The monoclonal antibody TH9 recognizes rat CD59. Rat CD59 was previously known as rat inhibitory protein (RIP) and it is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 regulates the formation and function of the lytic C5b-9 complex by binding C8 and preventing the unfolding and membrane insertion of C9 and by binding C9 and restricting its polymerization.CD59 is a small (18 – 25 kDa) molecule, linked to the cell membrane through a glycosyl phosphatidylinositol (GPI) anchor and comprising 77 amino acids with a single N-linked carbohydrate group at Asn-18. Analogues of CD59 can be found in all species with similar structures and sizes. In rat, CD59 is expressed on vacular endothelium and circulating cells. In the central nervous system (CNS) of the rat, CD59 is expressed on the Schwann sheath of peripheral nerve fibres and on ependymal cells, but not on glial cells and neurons in the CNS. Rat astrocytes in vitro express CD59 on its surface. CD59 may be involved in rheumatoid arthritis, motor nerve injury in the Guillain-Barré sydrome and in other diseases where defective inhibition of complement activation on self tissue is involved. Furthermore, CD59 may play an important part in abrogating the effects of complement attack in renal disease. Its presence and protective effect have already been demonstrated on human renal cells.
Host
Rat
Reactivity
Applications
Conjugation
CD59 Glycoprotein (CD59) Antibody (PE), Abbexa, abx270826
Protectin (CD59) Antibody (PE) is a Rabbit Polyclonal Antibody conjugated to PE against Protectin (CD59) for use in flow cytometry.
Host
Rabbit
Reactivity
Human
Applications
FCM
Conjugation
PE
CD59 Glycoprotein (CD59) Antibody (APC), Abbexa, abx139309
CD59 Antibody is a Mouse Monoclonal against CD59.
Host
Mouse
Reactivity
Human
Applications
FCM
Conjugation
APC
CD59 Glycoprotein (CD59) Antibody (Biotin), Abbexa, abx105247
CD59 glycoprotein Antibody (Biotin) is a Rabbit Polyclonal antibody against CD59 glycoprotein conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
CD59 Glycoprotein (CD59) Antibody (HRP), Abbexa, abx108082
CD59 Glycoprotein Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP against CD59 Glycoprotein. CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex (MAC), whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This inhibitor appears to be species-specific. This protein also plays a role in signal transduction for T-cell activation complexed to a protein tyrosine kinase. CD59 deficiency results in hemolytic anemia and thrombosis, which can lead to cerebral infarction.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
CD59 Glycoprotein (CD59) Antibody (APC), Abbexa, abx270594
Protectin (CD59) Antibody (APC) is a Rabbit Polyclonal Antibody conjugated to APC against Protectin (CD59) for use in flow cytometry.
Host
Rabbit
Reactivity
Human
Applications
FCM
Conjugation
APC
CD59 Glycoprotein (CD59) Antibody (FITC), Abbexa, abx106665
CD59 glycoprotein Antibody (FITC) is a Rabbit Polyclonal antibody against CD59 glycoprotein conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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