Search results for LEF1 antibody
Lymphoid Enhancer Binding Factor 1 (LEF1) Antibody, Abbexa, abx213777
LEF1 Antibody is a Rabbit Polyclonal against LEF1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Lymphoid Enhancer Binding Factor 1 (LEF1) Antibody, Abbexa, abx216546
Lymphoid Enhancer Binding Factor 1 (LEF1) Antibody is a Rabbit Polyclonal antibody for the detection of LEF1. Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity). Isoform 3 lacks the CTNNB1 interaction domain and may be an antagonist for Wnt signaling. Isoform 5 transcriptionally activates the fibronectin promoter, binds to and represses transcription from the E-cadherin promoter in a CTNNB1-independent manner, and is involved in reducing cellular aggregation and increasing cell migration of pancreatic cancer cells. Isoform 1 transcriptionally activates MYC and CCND1 expression and enhances proliferation of pancreatic tumor cells.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Lymphoid Enhancer Binding Factor 1 (LEF1) Antibody, Abbexa, abx213778
LEF1 Antibody is a Rabbit Polyclonal against LEF1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Lymphoid Enhancer Binding Factor 1 (LEF1) Antibody, Abbexa, abx000894
LEF1 Antibody is a Rabbit Polyclonal antibody against LEF1. Lymphoid enhancer-binding factor 1(LEF1) belongs to a family of regulatory protein share homology with high mobility group protein-1, and it's a nuclear protein exprssed in pre-B and T cells. LEF1 has a role in the Wnt signaling pathway and hair cell differentiation and follicle morphogenesis. Together with CTNNB1 and EP300, LEF1 activates transcription of target genes. Isoform 5 transcriptionally activates the fibronectin promoter, binds to and represses transcription from the E-cadherin promoter in a CTNNB1-independent manner, and is involved in reducing cellular aggregation and increasing cell migration of pancreatic cancer cells. Isoform 1 transcriptionally activates MYC and CCND1 expression and enhances proliferation of pancreatic tumor cells.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IF/ICC, IP
Conjugation
Unconjugated
Lymphoid Enhancer Binding Factor 1 (LEF1) Antibody, Abbexa, abx431385
LEF1 Antibody is a Goat Polyclonal antibody against LEF1.
Host
Goat
Reactivity
Human
Applications
P-ELISA, WB, IF/ICC, FCM
Conjugation
Unconjugated
Lymphoid Enhancer Binding Factor 1 (LEF1) Antibody, Abbexa, abx234745
LEF1 Antibody is a Rabbit Polyclonal against LEF1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IP
Conjugation
Unconjugated
Lymphoid Enhancer Binding Factor 1 (LEF1) Antibody, Abbexa, abx037788
Rabbit Polyclonal against the LEF1 protein.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Lymphoid Enhancer Binding Factor 1 (LEF1) Antibody, Abbexa, abx317879
LEF1 Antibody is a Rabbit Polyclonal against LEF1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Lymphoid Enhancer Binding Factor 1 (LEF1) Antibody, Abbexa, abx026579
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Lymphoid Enhancer-Binding Factor 1 (LEF1) Antibody, Abbexa, abx457398
Lymphoid Enhancer-Binding Factor 1 (LEF1) Antibody is a Rabbit polyclonal antibody for the detection of Human Lymphoid Enhancer-Binding Factor 1 (LEF1).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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