Search results for RAN antibody
GTP-Binding Nuclear Protein RAN (RAN) Antibody, Abbexa, abx000929
RAN Antibody is a Rabbit Polyclonal antibody against RAN. RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions, it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. RAN could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of RAN-GTP around chromatin which, in turn, induces the local nucleation of microtubules. RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor. Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy). RAN coactivation of the AR diminishes with polyglutamine expansion within the AR, and this weak coactivation may lead to partial androgen insensitivity during the development of Kennedy's disease.
Host
Rabbit
Reactivity
Mouse, Rat
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
GTP-Binding Nuclear Protein RAN (RAN) Antibody, Abbexa, abx242019
RAN Antibody is a Rabbit Polyclonal against RAN.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
GTP-Binding Nuclear Protein RAN (RAN) Antibody, Abbexa, abx032938
RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions, it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. RAN could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of RAN-GTP around chromatin which, in turn, induces the local nucleation of microtubules. RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor. Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy). RAN coactivation of the AR diminishes with polyglutamine expansion within the AR, and this weak coactivation may lead to partial androgen insensitivity during the development of Kennedy's disease.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
GTP-Binding Nuclear Protein RAN (RAN) Antibody, Abbexa, abx214680
RAN Antibody is a Rabbit Polyclonal against RAN.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
GTP-Binding Nuclear Protein RAN (RAN) Antibody, Abbexa, abx328361
RAN Antibody is a Rabbit Polyclonal against RAN.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
GTP-Binding Nuclear Protein RAN (RAN) Antibody, Abbexa, abx214681
RAN Antibody is a Rabbit Polyclonal against RAN.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
GTP-Binding Nuclear Protein RAN (RAN) Antibody, Abbexa, abx242241
RAN Antibody is a Rabbit Polyclonal against RAN.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
anti-Hamster (CHO) Ran Antibody - Affinity Purified, ICL, GRAN-65ALY-Z
This polyclonal antibody isdesigned for the specific detection of RAN, a GTP-binding nuclear protein, in Chinese Hamster Ovary (CHO) cells. RAN plays a critical role in nucleocytoplasmic transport and cell cycle regulation. Produced in goat and affinity-purified for high specificity, this antibody isideal for ELISA and Western blot applicationsin cell biology and host cell protein (HCP) analysis.Host Species:GoatTarget:RAN (CHO) – GTP-binding nuclear proteinClonality:PolyclonalIsotype:IgGApplications:ELISA, Western BlotFormat:Lyophilized, UnconjugatedBuffer:Phosphate buffered saline (PBS), pH 7.2 with stabilizerPurity:Antigen Affinity PurifiedStorage:2–8°CShelf Life:2 yearsCatalog #:GRAN-65ALY-ZOrigin:USA
Host
Goat
Reactivity
Hamster
Applications
ELISA, WB
Conjugation
Unconjugated
anti-Hamster (CHO) Ran Antibody - Affinity Purified, ICL, GRAN-65ALY
This polyclonal antibody isdesigned for the specific detection of RAN, a GTP-binding nuclear protein, in Chinese Hamster Ovary (CHO) cells. RAN is essential for nucleocytoplasmic transport and cell cycle regulation. Produced in goat and affinity-purified for high specificity, this antibody isideal for ELISA and Western blot applications in molecular and cellular biology research.Host Species:GoatTarget:RAN (CHO) – GTP-binding nuclear proteinClonality:PolyclonalIsotype:IgGApplications:ELISA, Western BlotFormat:Lyophilized, UnconjugatedBuffer:Phosphate buffered saline (PBS), pH 7.2 with stabilizerPurity:Antigen Affinity PurifiedStorage:2–8°CShelf Life:2 yearsCatalog #:GRAN-65ALYOrigin:USA
Host
Goat
Reactivity
Hamster
Applications
ELISA, WB
Conjugation
Unconjugated
GTP-Binding Nuclear Protein RAN (RAN) Antibody, Abbexa, abx119043
RAN Antibody is a Rabbit Polyclonal antibody against RAN.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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