Search results for Raf1 antibody
Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody, Abbexa, abx237088
RAF1 Antibody is a Rabbit Polyclonal against RAF1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody, Abbexa, abx218161
Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody is a Rabbit Polyclonal antibody for the detection of RAF1. Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2). The phosphorylated form of RAF1 (on residues Ser-338 and Ser-339, by PAK1) phosphorylates BAD/Bcl2-antagonist of cell death at 'Ser-75'. Phosphorylates adenylyl cyclases: ADCY2, ADCY5 and ADCY6, resulting in their activation. Phosphorylates PPP1R12A resulting in inhibition of the phosphatase activity. Phosphorylates TNNT2/cardiac muscle troponin T. Can promote NF-kB activation and inhibit signal transducers involved in motility (ROCK2), apoptosis (MAP3K5/ASK1 and STK3/MST2), proliferation and angiogenesis (RB1). Can protect cells from apoptosis also by translocating to the mitochondria where it binds BCL2 and displaces BAD/Bcl2-antagonist of cell death. Regulates Rho signaling and migration, and is required for normal wound healing. Plays a role in the oncogenic transformation of epithelial cells via repression of the TJ protein, occludin (OCLN) by inducing the up-regulation of a transcriptional repressor SNAI2/SLUG, which induces down-regulation of OCLN. Restricts caspase activation in response to selected stimuli, notably Fas stimulation, pathogen-mediated macrophage apoptosis, and erythroid differentiation.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody, Abbexa, abx328547
RAF1 Antibody is a Rabbit Polyclonal against RAF1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody, Abbexa, abx305042
RAF1 Antibody is a Rabbit Polyclonal against RAF1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC, IP
Conjugation
Unconjugated
Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody, Abbexa, abx323235
RAF1 Antibody is a Rabbit Polyclonal against RAF1.
Host
Rabbit
Reactivity
Human
Applications
WB, IHC
Conjugation
Unconjugated
Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody, Abbexa, abx122947
Rabbit Polyclonal against the RAF1 protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody, Abbexa, abx329894
RAF1 Antibody is a Rabbit Polyclonal against RAF1.
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody (Biotin), Abbexa, abx305045
RAF1 Antibody (Biotin) is a Rabbit Polyclonal against RAF1 conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Raf Proto-Oncogene Serine/Threonine Protein Kinase (RAF1) Antibody (HRP), Abbexa, abx305043
RAF1 Antibody (HRP) is a Rabbit Polyclonal against RAF1 conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
![Alexa Fluor® 555 Anti-Raf1 antibody [EP4969] - N-terminal Brand Logo](https://file.buyantibody.com/public/brand/20260608/Abcam.jpg "Click to View Alexa Fluor® 555 Anti-Raf1 antibody [EP4969] - N-terminal Product Detail")
Alexa Fluor® 555 Anti-Raf1 antibody [EP4969] - N-terminal, Abcam, AB313196
Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . How are conjugated primary antibodies validated? This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling. For suitable applications and species reactivity, please refer to the unconjugated version of this clone.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Target Binding Affinity, Antibody Labelling, ICC/IF, Flow Cyt (Intra)
Conjugation
Alexa Fluor® 555
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