Search results for TNFAIP3 antibody
Tumor Necrosis Factor Alpha Induced Protein 3 (TNFAIP3) Antibody, Abbexa, abx325696
TNFAIP3 Antibody is a Rabbit Polyclonal against TNFAIP3.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Tumor Necrosis Factor Alpha Induced Protein 3 (TNFaIP3) Antibody, Abbexa, abx128176
Tumor Necrosis Factor Alpha Induced Protein 3 Antibody is a Rabbit Polyclonal against Tumor Necrosis Factor Alpha Induced Protein 3.
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Tumor Necrosis Factor Alpha-Induced Protein 3 (TNFAIP3) Antibody, Abbexa, abx238818
TNFAIP3 Antibody is a Rabbit Polyclonal against TNFAIP3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Tumor Necrosis Factor Alpha-Induced Protein 3 (TNFAIP3) Antibody, Abbexa, abx147829
Tumor Necrosis Factor Alpha-Induced Protein 3 (TNFAIP3) Antibody is a Rabbit Polyclonal antibody for the detection of TNFAIP3. Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. In cooperation with TAX1BP1 promotes disassembly of E2-E3 ubiquitin protein ligase complexes in IL-1R and TNFR-1 pathways; affected are at least E3 ligases TRAF6, TRAF2 and BIRC2, and E2 ubiquitin-conjugating enzymes UBE2N and UBE2D3. In cooperation with TAX1BP1 promotes ubiquitination of UBE2N and proteasomal degradation of UBE2N and UBE2D3. Upon TNF stimulation, deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF-or LPS-mediated activation of NF-kappa-B. Deubiquitinates TRAF6 probably acting on 'Lys-63'-linked polyubiquitin. Upon T-cell receptor (TCR) -mediated T-cell activation, deubiquitinates 'Lys-63'-polyubiquitin chains on MALT1 thereby mediating disassociation of the CBM (CARD11:BCL10:MALT1) and IKK complexes and preventing sustained IKK activation. Deubiquitinates NEMO/IKBKG; the function is facilitated by TNIP1 and leads to inhibition of NF-kappa-B activation. Upon stimulation by bacterial peptidoglycans, probably deubiquitinates RIPK2. Can also inhibit I-kappa-B-kinase (IKK) through a non-catalytic mechanism which involves polyubiquitin; polyubiquitin promotes association with IKBKG and prevents IKK MAP3K7-mediated phosphorylation. Targets TRAF2 for lysosomal degradation. In vitro able to deubiquitinate 'Lys-11'-, 'Lys-48'-and 'Lys-63' polyubiquitin chains. Inhibitor of programmed cell death. Has a role in the function of the lymphoid system. Required for LPS-induced production of proinflammatory cytokines and IFN beta in LPS-tolerized macrophages.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Tumor Necrosis Factor Alpha-Induced Protein 3 (TNFAIP3) Antibody (Biotin), Abbexa, abx315352
TNFAIP3 Antibody (Biotin) is a Rabbit Polyclonal against TNFAIP3 conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Tumor Necrosis Factor Alpha-Induced Protein 3 (TNFAIP3) Antibody (FITC), Abbexa, abx315351
TNFAIP3 Antibody (FITC) is a Rabbit Polyclonal against TNFAIP3 conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
Tumor Necrosis Factor Alpha-Induced Protein 3 (TNFAIP3) Antibody (HRP), Abbexa, abx315350
TNFAIP3 Antibody (HRP) is a Rabbit Polyclonal against TNFAIP3 conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
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