Search results for receptor tyrosine kinase

Discoidin Domain Receptor Tyrosine Kinase 2 (DDR2) Antibody, Abbexa, abx025427
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq]. This antibody is supplied as crude ascites.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated

Erb-B2 Receptor Tyrosine Kinase 2 (ERBB2) Antibody, Abbexa, abx159491
ERBB2 Antibody is a Mouse Monoclonal against ERBB2.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

Discoidin Domain Receptor Tyrosine Kinase 2 (DDR2) Antibody, Abbexa, abx010632
DDR2 (discoidin domain receptor family, member 2) is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated

Discoidin Domain Receptor Tyrosine Kinase 2 (DDR2) Antibody, Abbexa, abx135978
DDR2 Antibody is a Rabbit Polyclonal against DDR2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated

Erb-B2 Receptor Tyrosine Kinase 4 (ERBB4) Antibody, Abbexa, abx241511
ERBB4 Antibody is a Rabbit Polyclonal against ERBB4.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated

Erb-B2 Receptor Tyrosine Kinase 2 (ERBB2) Antibody, Abbexa, abx159490
ERBB2 Antibody is a Mouse Monoclonal against ERBB2.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated

Erb-B2 Receptor Tyrosine Kinase 4 (ERBB4) Antibody, Abbexa, abx241764
ERBB4 Antibody is a Rabbit Polyclonal against ERBB4.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Antibody (Biotin), Abbexa, abx335954
NTRK1 Antibody (Biotin) is a Rabbit Polyclonal against NTRK1.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin

Discoidin Domain Receptor Tyrosine Kinase 1 (DDR1) Antibody, Abbexa, abx140511
CD167a Antibody is a Mouse Monoclonal against CD167a.
Host
Mouse
Reactivity
Human
Applications
FCM, IP
Conjugation
Unconjugated

Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Antibody (FITC), Abbexa, abx335953
NTRK1 Antibody (FITC) is a Rabbit Polyclonal against NTRK1.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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