Search results for db

Goat Anti-Mouse IgG H&L Polyclonal Antibody, HRP, AntibodySystem, PMB96431

Goat Anti-Human IgG H&L Polyclonal Antibody, ALP, AntibodySystem, PHB96433

Goat Anti-Human IgG H&L Polyclonal Antibody, AntibodySystem, PHB96411

Goat Anti-Rabbit IgG H&L Polyclonal Antibody, AntibodySystem, PTB96411

Goat Anti-Chicken IgY Polyclonal Antibody, AntibodySystem, PCC09211

Anti-DNA-RNA Hybrid Antibody(S9.6), AntibodySystem, RGK60001

DNA-RNA hybrids are a natural occurrence within eukaryotic cells and their level are high at sites of high transcriptional activity. They are non-canonical nucleic acid structures with transcriptional regulatory functions. Their presence is reported to predispose a locus to chromosomal breakage. A locus forming an DNA:RNA creates a double-stranded A/B intermediate conformation, with a second target for single-stranded nucleic acid binding proteins on the complementary, displaced DNA strand. They are shown to be resistant to the activity of DNA methyltransferases. The formation of DNA:RNA hybrids has been associated with a number of neurological diseases. Mutations in the DNA:RNA helicase senataxin (SETX) are implicated in the dominant juvenile form of amyotrophic lateral sclerosis type 4 and a recessive form of ataxia oculomotor apraxia type 2.

Anti-Human FOCAD Polyclonal Antibody, AntibodySystem, PHK18701

Anti-DNA Antibody (17s.74), AntibodySystem, RGK23801

Anti-DNA Antibody (83.22), AntibodySystem, RGK23802

Anti-DNA Antibody (111.1), AntibodySystem, RGK23803