Search results for 12

Kelch-Like Protein 12 (KLHL12) Antibody, Abbexa, abx011511

Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.

Human Protocadherin-12 (PCDH12) ELISA Kit, Abbexa, abx537954

Human Protocadherin-12 (PCDH12) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Protocadherin-12 (PCDH12) concentrations in serum, plasma and other biological fluids.

A Kinase Anchor Protein 12 (AKAP12) Antibody, Abbexa, abx323132

AKAP12 Antibody is a Rabbit Polyclonal against AKAP12.

Anti-LRRK2 antibody [UDD3 30(12)], Abcam, AB133518

In recent years, a critical need in the Parkinson's Disease (PD) research community has been access to well-characterized antibodies that can be used to efficiently detect and purify Leucine-Rich Repeat Kinase 2 (LRRK2) protein. The Michael J. Fox Foundation (MJFF) has supported this effort by partnering with Dr. Dario Alessi (MRC Protein Phosphorylation Unit, University of Dundee) to help accelerate LRRK2 research. Dr. Alessi has characterized unique and high quality LRRK2 rabbit monoclonal antibodies, generated by Epitomics, to be made widely available for PD research community. LRRK2 (Leucine-rich repeat kinase 2, dardarin) is a multi-domain protein belonging to the ROCO family of proteins that contains a kinase and GTPase domain among its many protein interaction domains. LRRK2 is mutated in a significant number of Parkinson's disease (PD) patients. Mutations in this gene account for 4% of PD, and are observed in 1% of sporadic PD patients. The most common mutation replaces glycine 2019 with a serine that results in increased LRRK2 kinase activity. This indicates that inhibitors of LRRK2 kinase activity might be of therapeutic benefit for the treatment of Parkinson's disease and has stimulated much activity in this field of research. The Dundee-MJFF LRRK2[100-500] total antibody will be of great utility in further understanding LRRK2 as it relates to Parkinson's disease. It should be noted this antibody is highly selective and sensitive and can readily be used to monitor LRRK2 protein levels in immunoblot analysis of 2-20 microgram amounts of whole cell extract. The LRRK2[100-500] total antibody recognizes both mouse and human endogenous LRRK2. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Collaborations This antibody was developed with support from The Michael J. Fox Foundation.

Pepsinogen I antibody [8003 (99/12)], Genetex, GTX39440

Hamster Interleukin 12 (IL12) ELISA Kit, Abbexa, abx257598

Hamster Interleukin 12 (IL12) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Hamster IL12 concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Alpha fetoprotein / AFP antibody [MBS-12], Genetex, GTX34408

Mouse Lipocalin 12 (LCN12) ELISA Kit, Abbexa, abx518194

Mouse Lipocalin 12 (LCN12) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Epididymal-specific lipocalin-12 concentrations in serum, plasma and other biological fluids.

A Disintegrin And Metalloproteinase With Thrombospondin 12 (ADAMTS12) Antibody, Abbexa, abx104713

Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 12 (ADAMTS12).

Human Cholecystokinin 12 (CCK12) ELISA Kit, Abbexa, abx151055

Human Cholecystokinin 12 (CCK12) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Cholecystokinin 12 (CCK12) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Cholecystokinin 12 (CCK12)No significant cross-reactivity or interference between Cholecystokinin 12 (CCK12) and analogues was observed.