Search results for Catalytic subunit
5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 (PRKAA2) Antibody, Abbexa, abx326940
PRKAA2 Antibody is a Rabbit Polyclonal against PRKAA2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated
5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 (PRKAA2) Antibody, Abbexa, abx025250
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. This antibody is supplied as crude ascites.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-1 (PRKAA1) Antibody, Abbexa, abx038226
Rabbit Polyclonal against the PRKAA1 protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma Isoform (PIK3CG) Antibody, Abbexa, abx033934
PIK3CG belongs to the pi3/pi4-kinase family of proteins. It is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene for this protein is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-1 (PRKAA1) Antibody, Abbexa, abx317891
PRKAA1 Antibody is a Rabbit Polyclonal against PRKAA1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta Isoform (PI3KCD) Antibody, Abbexa, abx033821
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma Isoform (PIK3CG) Antibody, Abbexa, abx146525
Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma Isoform (PIK3CG) Antibody is a Rabbit Polyclonal antibody for the detection of PIK3CG. Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha 2 (PRKAA2) Antibody, Abbexa, abx455558
5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha 2 (PRKAA2) Antibody is a Rabbit polyclonal antibody for the detection of Human 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha 2 (PRKAA2).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA) Antibody, Abbexa, abx402315
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human, Mouse PIK3CA.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
DNA-Dependent Protein Kinase Catalytic Subunit Phospho-Thr2609 (PRKDC pT2609) Antibody, Abbexa, abx032004
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Stem cell surface receptors and activate yeast MAPK pathway.
Host
Rabbit
Reactivity
Human
Applications
ELISA, DB
Conjugation
Unconjugated
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