Search results for histone deacetylase A

Histone Deacetylase 8 (HDAC8) Antibody, Abbexa, abx457000
Histone Deacetylase 8 (HDAC8) Antibody is a Rabbit polyclonal antibody for the detection of Human Histone Deacetylase 8 (HDAC8).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

Histone Deacetylase 4 (HDAC4) Antibody, Abbexa, abx109875
Histone deacetylase 4 Antibody is a Rabbit Polyclonal antibody against Histone deacetylase 4.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated

Histone Deacetylase 6 (HDAC6) Antibody, Abbexa, abx026070
HDAC6 (histone deacetylase 6) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin, and has been shown to interact with HDAC11, SIRT2, and F-actin. HDAC6 is ubiquitinated, but its polyubiquitination however does not lead to degradation. HDAC is also a potential target of sumoylation.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

Histone Deacetylase 6 (HDAC6) Antibody, Abbexa, abx457345
Histone Deacetylase 6 (HDAC6) Antibody is a Rabbit polyclonal antibody for the detection of Human Histone Deacetylase 6 (HDAC6).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

Histone Deacetylase 7 (HDAC7) Antibody, Abbexa, abx005492
HDAC7 Antibody is a Rabbit Polyclonal antibody against HDAC7. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IF/ICC
Conjugation
Unconjugated

Histone Deacetylase 3 (HDAC3) Antibody, Abbexa, abx010929
Histone Deacetylase 3 (HDAC3) Antibody is a Rabbit Polyclonal antibody for the detection of HDAC3. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

Histone Deacetylase 1 (HDAC1) Antibody, Abbexa, abx038462
Rabbit Polyclonal against the HDAC1 protein.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated

Histone Deacetylase 3 (HDAC3) Antibody, Abbexa, abx013105
Rabbit polyclonal antibody against HDAC3 protein. Immunogen region is C-terminal.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated

Histone Deacetylase 11 (HDAC11) Antibody, Abbexa, abx026098
HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

Histone Deacetylase 2 (HDAC2) Antibody, Abbexa, abx037620
Rabbit Polyclonal against the HDAC2 protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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