Search results for 2932

Phospho-GSK3 beta (Ser9) Antibody (YA193)(PBS only), MedChemexpress, HY-P80820A

Phospho-GSK3 beta (Ser9) Antibody (YA193) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-GSK3 beta (Ser9).

Phospho-GSK3β-S9 Rabbit mAb- ABclonal, ABclonal, AP1088

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx010856

Glycogen synthase kinase 3 (GSK-3), a serine-threonine kinase with two isoforms (alpha and beta), was originally discovered as a key enzyme in glycogen metabolism. GSK-3 was subsequently shown to function in cell division, proliferation, motility and survival. GSK-3 plays a role in a number of pathological conditions including cancer and diabetes and is increasingly seen as an important component of neurological diseases. GSK-3 phosphorylates tau and presenilin-1, which are involved in the development of Alzheimer's disease. Both isoforms of GSK-3 are ubiquitously expressed, although particularly high levels of GSK-3 beta are found in the brain where it is involved in synaptic plasticity, possibly via regulation of NMDA receptor trafficking. GSK-3 phosphorylates over 40 different substrates including signaling proteins, transcription factors and structural proteins, and is part of the signal transduction cascade of a large number of growth factors and cytokines. The activity of GSK is regulated by phosphorylation (Akt: Akt-mediated phosphorylation at Ser21 of GSK-3 alpha and Ser9 of GSK-3 beta, S6K, RSK, PKA and PKC), dephosphorylation (PP1 and PP2A), and by binding to protein complexes (with beta catenin, axin, CK1 and the APC complex).

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx318062

GSK3B Antibody is a Rabbit Polyclonal against GSK3B.

GSK3 beta antibody [3D10], Genetex, GTX83315

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody (Biotin), Abbexa, abx304086

GSK3B Antibody (Biotin) is a Rabbit Polyclonal against GSK3B conjugated to Biotin.