Search results for ACE2 antibody
Angiotensin-Converting Enzyme 2 (ACE2) Antibody, Abbexa, abx214857
ACE2 Antibody is a Rabbit Polyclonal against ACE2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Angiotensin Converting Enzyme 2 (ACE2) Antibody, Abbexa, abx230011
Angiotensin Converting Enzyme 2 (ACE2) is a Rabbit Polyclonal antibody for the detection of Angiotensin Converting Enzyme 2 (ACE2). The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Angiotensin Converting Enzyme 2 (ACE2) Antibody, Abbexa, abx032686
ACE2 cDNA encodes a deduced 805-amino acid protein containing a potential 17-amino acid N-terminal signal peptide and a putative 22-amino acid C-terminal membrane anchor. It also possesses a zinc metalloprotease consensus sequence and a conserved glutamine residue that may function as a third zinc ligand. ACE2 is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE converts angiotensin I to angiotensin II, ACE2 converts angiotensin I to angiotensin 1-9, which has 9 amino acids. Angiotensin II is a potent blood vessel constrictor, while angiotensin 1-9 does not impact blood vessels but is cleaved by ACE to a shorter peptide, angiotensin 1-7, which is a blood vessel dilator. Spike (S) proteins of coronaviruses, including the SARS coronavirus, bind with cellular receptors to mediate infection of target cells. ACE2 binds the S1 domain of the SARS coronavirus S protein. SARS coronavirus replicates efficiently on ACE2-transfected but not mock-transfected 293T cells. Anti-ACE2 but not anti-ACE1 antibody blocks viral replication on Vero E6 cells. It has been proposed that ACE2 is a functional receptor for SARS coronavirus.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
Angiotensin-Converting Enzyme 2 (ACE2) Antibody, Abbexa, abx403765
Rat Angiotensin-Converting Enzyme 2 (ACE2) Antibody is a Mouse monoclonal against Angiotensin-Converting Enzyme 2 (ACE2).
Host
Mouse
Reactivity
Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Angiotensin Converting Enzyme 2 (ACE2) Antibody, Abbexa, abx376502
Angiotensin Converting Enzyme 2 (ACE2) Antibody is a Mouse Monoclonal antibody for the detection of Human ACE2.
Host
Mouse
Reactivity
Human
Applications
WB, IHC
Conjugation
Unconjugated
Angiotensin-Converting Enzyme 2 (ACE2) Antibody, Abbexa, abx275096
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Angiotensin-Converting Enzyme 2 (ACE2) Antibody is a Rabbit Monoclonal against Human ACE2.
Host
Rabbit
Reactivity
Human
Applications
FCM
Conjugation
Unconjugated
Angiotensin-Converting Enzyme 2 (ACE2) Antibody, Abbexa, abx456632
Angiotensin-Converting Enzyme 2 (ACE2) Antibody is a Rabbit polyclonal antibody for the detection of Mouse Angiotensin-Converting Enzyme 2 (ACE2).
Host
Rabbit
Reactivity
Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Angiotensin-Converting Enzyme 2 (ACE2) Antibody, Abbexa, abx275094
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Angiotensin-Converting Enzyme 2 (ACE2) Antibody is a Rabbit Monoclonal against Human ACE2.
Host
Rabbit
Reactivity
Human
Applications
FCM
Conjugation
Unconjugated
Angiotensin-converting enzyme 2 (ACE2) Antibody, Abbexa, abx457723
Angiotensin-converting enzyme 2 (ACE2) Antibody is a monoclonal Mouse antibody for the detection of ACE2.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Angiotensin-Converting Enzyme 2 (ACE2) Antibody, Abbexa, abx034794
Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
Host
Mouse
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
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