Search results for C9

Esrp-1/2 antibody [23A7.C9], Genetex, GTX48760

C9 neoantigen, Human, mAb WU13-15, Hycult Biotech, HM2264

The monoclonal antibody WU13-15 recognizes a neoepitope on the 61 kDa complement component C9, integrated in the terminal complement complex (TCC). The complement system is an ancient proinflammatory and microbial destruction system, that may be considered part of both the innate and adaptive immune systems. It consists of the classical, alternative, and lectin-binding pathways. Each pathway is triggered in a distinct manner, yet all deposit C3 fragments on a target and engage a common terminal sequence called TCC or the “membrane attack complex” (MAC). In contrast to the activation pathways, which require enzymatic cleavage for activation, the terminal pathway relies on conformational changes induced by binding of the different subunits. TCC is composed of a complex of four complement proteins (C5b, C6, C7, and C8) which bind to the outer surface of the target plasma membrane, and many copies of a fifth protein (C9) that hookup to one another, forming a ring in the membrane. The ring structure formed by C9 is a pore in the membrane that allows free diffusion of molecules in and out of the cell. If enough pores form, the cell is no longer able to survive. The membrane attack complex is initiated when the complement protein, C5 convertase, cleaves C5 into C5a and C5b. Binding of C6 facilitates binding of C7 which alters the conformation of the complex. After binding of C8, a variable number of C9 molecules associate with the C5b678 complex, together constituting TCC. The formation of TCC causes lysis of cells or can trigger a variety of cellular metabolic pathways resulting in the synthesis and release of inflammatory mediators. TCC contains neoantigens that are absent in the individual native C9 proteins. Neoantigens are present both in the membranebound (MAC) and the fluid phase (SC5b-9) complex. TCC is present in normal human plasma and increases upon complement activation.

Homeobox Protein Hox-C9 (HOXC9) Antibody, Abbexa, abx304170

HOXC9 Antibody is a Rabbit Polyclonal against HOXC9.

Anti-RBM35A + RBM35B antibody [23A7.C9], Abcam, AB106555

Homeobox Protein Hox-C9 (HOXC9) Antibody, Abbexa, abx027944

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Complement Component 9 (C9) Antibody (HRP), Abbexa, abx312618

C9 Antibody (HRP) is a Rabbit Polyclonal against C9 conjugated to HRP.

BRAP antibody [1E7-C9-D10-B10], Genetex, GTX16484

Complement Component 9 (C9) Antibody Pair, Abbexa, abx370547

Complement Component 9 (C9) Antibody Pair for use in Sandwich ELISA assay development. This antibody pair contains: Component 5 × 96 tests 10 × 96 tests Capture Antibody200 µg 400 µg Biotin-Conjugated Detection Antibody 50 µg 100 µg Standard 2 µg 10 µg Please note that quantities and concentrations may change between different batches. It is recommended to use this antibody pair with abx098958 Antibody Pair Support Kit (Sandwich Method).

Complement Component 9 (C9) Antibody Pair, Abbexa, abx370752

Complement Component 9 (C9) Antibody Pair for use in Sandwich ELISA assay development. This antibody pair contains: Component 5 × 96 tests 10 × 96 tests Capture Antibody200 µg 400 µg Biotin-Conjugated Detection Antibody 50 µg 100 µg Standard 2 µg 10 µg Please note that quantities and concentrations may change between different batches. It is recommended to use this antibody pair with abx098958 Antibody Pair Support Kit (Sandwich Method).

Alpha B Crystallin (3A10.C9) antibody, Covalab, Ref 00096525