Search results for Cellular tumor antigen p53
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx325017
TP53 Antibody is a Rabbit Polyclonal against TP53.
Host
Rabbit
Reactivity
Human, Monkey
Applications
ELISA, WB
Conjugation
Unconjugated
Cellular Tumor Antigen P53 (TP53) Antibody, Abbexa, abx422674
Cellular Tumor Antigen P53 (TP53) Antibody is a Mouse monoclonal against Cellular Tumor Antigen P53 (TP53).
Host
Mouse
Reactivity
Human, Mouse, Rat
Applications
IHC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx339990
TP53 Antibody is a Rabbit Polyclonal against TP53.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx031604
p53 (Sumoylation Site Specific) Antibody is a Rabbit Polyclonal antibody against p53. Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. P53 is subject to modification by conjugation of SUMO-1. A p53 mutant deficient for MDM2 binding is poorly sumoylated in vivo compared to wild-type p53. Overexpression of MDM2 increases the level of p53 sumoylation, which is further stimulated by expression of ARF. These results show that p53 sumoylation is regulated by MDM2 and ARF-mediated nucleolar targeting.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx236083
P53 Antibody is a Rabbit Polyclonal against P53.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx402111
Cellular Tumor Antigen p53 (TP53) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human TP53.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx013359
Rabbit polyclonal antibody against p53 protein. Immunogen region is C-terminal.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx461408
Cellular Tumor Antigen p53 (TP53) Antibody is a monoclonal Nanobody expressed in CHO cells for the detection of Human TP53.
Host
CHO cells
Reactivity
Human
Applications
ELISA, IP
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx034681
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Cellular Tumor Antigen p53 (TP53) Antibody, Abbexa, abx227079
Cellular Tumor Antigen p53 (TP53) Antibody is a Rabbit Monoclonal antibody for the detection of p53.
Host
Rabbit
Reactivity
Human
Applications
IHC
Conjugation
Unconjugated
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