Search results for EPHA2

EPH Receptor A2 (EphA2) Antibody, Abbexa, abx033513

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

EPH Receptor A2 (EPHA2) Antibody, Abbexa, abx137439

EPH Receptor A2 (EPHA2) Antibody is a Mouse Monoclonal antibody against EPH Receptor A2 (EPHA2).

Anti-Mouse EPHA2 Polyclonal Antibody, AntibodySystem, PMD82401

EPH Receptor A2 (EphA2) Antibody, Abbexa, abx010719

EPH receptor A2 (EphA2), with 976-amino acid protein (about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA1, EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8, EphA10, EphB1, EphB2, EphB3, EphB4 and EphB6 are Eph family receptors for Ephrin family ligands. In normal cells, EphA2 negatively regulates cell growth and invasiveness. EphA2 is overexpressed by many human cancers, and is often associated with poor prognostic features. The clinical significance of the expression of EphA2 was observed in breast, prostate, colon, skin, cervical, ovarian, and lung cancers.EphA2 may serve as a novel target for bladder cancer, colonic adenocarcinoma and ovarian cancer therapy.

Phospho-EPHA2-S897 Rabbit mAb- ABclonal, ABclonal, AP1516

EPHA2 / EPHA3 / EPHA4 (pY588 / 596) Antibody, Abbexa, abx328084

EPHA2/EPHA3/EPHA4 (pY588/596) Antibody is a Rabbit Polyclonal against EPHA2/EPHA3/EPHA4 (pY588/596).

Phospho-EPHA2-S897 Rabbit pAb- ABclonal, ABclonal, AP1082

EPHA2 / EPHA3 / EPHA4 (pY588 / 596) Antibody, Abbexa, abx332970

EPHA2/EPHA3/EPHA4 (pY588/596) Antibody is a Rabbit Polyclonal against EPHA2/EPHA3/EPHA4 (pY588/596).

EPHA2 / 3 (Phospho-Tyr588 / 596) Antibody, Abbexa, abx012482

Rabbit polyclonal antibody against EPHA2/3 protein. Immunogen region is Internal. Specificity is as follows for the reactive species: H:Y588/Y596M:Y589/Y596, R:-/Y597.

Ephrin Type-A Receptor 2 (EPHA2) Antibody, Abbexa, abx421779

Ephrin Type-A Receptor 2 (EPHA2) Antibody is a Mouse Monoclonal antibody for the detection of Ephrin Type-A Receptor 2 (EPHA2) in Human samples.