Search results for F8

Coagulation Factor VIII (F8) Antibody, Abbexa, abx015745

F8, coagulation factor VIII, procoagulant component.This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa.This gene produces two alternatively spliced transcripts.Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex.This protein undergoes multiple cleavage events.Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc.This binding domain is essential for coagulant activity.Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Influenza A virus Nucleoprotein antibody [F8], Genetex, GTX40249

Coagulation Factor VIII (F8) Antibody (FITC), Abbexa, abx271186

Coagulation Factor VIII (F8) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC against Coagulation Factor VIII (F8).

Coagulation Factor VIII (F8) Antibody (Biotin), Abbexa, abx271452

Coagulation Factor VIII (F8) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Coagulation Factor VIII (F8).

Coagulation Factor VIII (F8) Antibody (HRP), Abbexa, abx303799

F8 Antibody (HRP) is a Rabbit Polyclonal against F8 conjugated to HRP.

Coagulation Factor VIII (F8) Antibody (Biotin), Abbexa, abx274552

Coagulation Factor VIII (F8) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Coagulation Factor VIII (F8).

Coagulation Factor VIII (F8) Antibody (FITC), Abbexa, abx271108

Coagulation Factor VIII (F8) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC against Coagulation Factor VIII (F8).

Anti-CoV-S2 domain (F8) antibody, ProteoGenix, PTXCOV-A541D

Description of Anti-CoV-S2 domain (F8) antibody General information on Anti-CoV-S2 domain (F8) antibody The spike glycoprotein of coronaviruses has been extensively studied since the emergence of the extremely virulent strains SARS-CoV and MERS-CoV. These studies have been crucial for increasing our knowledge and understanding of the pathology caused by the new strain of coronavirus, SARS-CoV-2. Despite the phylogenetic proximity between this strain and the etiological agent of the severe acute respiratory syndrome coronavirus (SARS) disease, significant differences were found in terms of infectivity between the two. More specifically, the presence of a furin cleavage site between the N-terminal region ( S1 subunit ) and the C-terminal ( S2 subunit ) alongside the presence of compensatory mutations is believed to have contributed to the higher overall infectivity in SARS-CoV-2. After the spike binds to the human receptor ACE2, it suffers important modifications including the proteolytic cleavage catalyzed by the ubiquitous human furin proteases and the conformational reorganization driven by the two heptad repeats, HR1 and HR2. The anti-CoV-S2 (F8) antibody is a fully human IgG immunoglobulin shown to strongly bind to the S2 subunit of the spike. The antibody was isolated from a vast pool of COVID-19 human antibodies (LiAb-SFCOVID-19™) via phage display. Moreover, its stability and ease of production have been established by transient expression in the CHO-based mammalian recombinant system – XtenCHO™. This antibody and similar products obtained from the COVID-19 human library have all been validated for ELISA applications using purified forms of the SARS-CoV-2 S2 protein.

Coagulation Factor VIII (F8) Antibody (FITC), Abbexa, abx274489

Coagulation Factor VIII (F8) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC against Coagulation Factor VIII (F8).

Coagulation Factor VIII (F8) Antibody (FITC), Abbexa, abx303800

F8 Antibody (FITC) is a Rabbit Polyclonal against F8 conjugated to FITC.