Search results for FADD
CASP8 And FADD Like Apoptosis Regulator (CFLAR) Antibody, Abbexa, abx324522
CFLAR Antibody is a Rabbit Polyclonal against CFLAR.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
CASP8 And FADD Like Apoptosis Regulator (CFLAR) Antibody, Abbexa, abx339604
CFLAR Antibody is a Rabbit Polyclonal against CFLAR.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
FAS-Associated Death Domain Protein (FADD) Antibody, Abbexa, abx324721
FADD Antibody is a Rabbit Polyclonal against FADD.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
FAS-Associated Death Domain Protein (FADD) Antibody, Abbexa, abx031108
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
FAS-Associated Death Domain Protein (FADD) Antibody, Abbexa, abx019082
FADD Antibody is a Rabbit Polyclonal antibody against Mouse.
Host
Rabbit
Reactivity
Mouse
Applications
WB
Conjugation
Unconjugated
CASP8 And FADD Like Apoptosis Regulator (CFLAR) Antibody, Abbexa, abx015815
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8.However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8.Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
CASP8 And FADD Like Apoptosis Regulator (CFLAR) Antibody, Abbexa, abx034233
Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. It lacks enzymatic (caspase) activity.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
CASP8 And FADD Like Apoptosis Regulator (CFLAR) Antibody, Abbexa, abx323810
CFLAR Antibody is a Rabbit Polyclonal against CFLAR.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
CASP8 And FADD Like Apoptosis Regulator (CFLAR) Antibody, Abbexa, abx213232
CFLAR Antibody is a Rabbit Polyclonal against CFLAR.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
FAS-Associated Death Domain Protein (FADD) Antibody, Abbexa, abx339812
FADD Antibody is a Rabbit Polyclonal against FADD.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
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