Search results for Hexokinase
Hexokinase 2 (HK2) Antibody, Abbexa, abx033901
In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase activity is involved in the first step in several metabolic pathways. HK3 is bound to the outer mitochondrial membrane. Its hydrophobic N-terminal sequence may be involved in membrane bindng. It is the predominant hexokinase isozyme expressed in insuline-responsive tissues such as skeletal muscle. The N and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus. Although found in NIDDM patients, genetic variations of HK2 do not contribute to the disease.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Hexokinase-4 (GCK) Antibody, Abbexa, abx033753
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of the gene for GCK results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in the gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), also called maturity onset diabetes of the young, type 2 (MODY2) ; mutations have also been associated with persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Hexokinase 2 (HK2) Antibody, Abbexa, abx100804
Polyclonal Antibody to Hexokinase 2 (HK2).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Hexokinase-4 (GCK) Antibody, Abbexa, abx321462
GCK Antibody is a Rabbit Polyclonal against GCK.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Hexokinase 3 (HK3) Antibody, Abbexa, abx324737
HK3 Antibody is a Rabbit Polyclonal against HK3.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Hexokinase-1 (HK1) Antibody, Abbexa, abx274887
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Hexokinase-1 (HK1) Antibody is a Rabbit Polyclonal against Human HK1.
Host
Rabbit
Reactivity
Human
Applications
FCM
Conjugation
Unconjugated
Hexokinase-1 (HK1) Antibody, Abbexa, abx100803
Polyclonal Antibody to Hexokinase-1 (HK1).
Host
Rabbit
Reactivity
Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Hexokinase-1 (HK1) Antibody, Abbexa, abx112999
Hexokinase-1 Antibody is a Rabbit Polyclonal antibody against Hexokinase-1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Hexokinase-1 (HK1) Antibody, Abbexa, abx214586
HK1 Antibody is a Rabbit Polyclonal against HK1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Hexokinase-1 (HK1) Antibody, Abbexa, abx329456
HK1 Antibody is a Rabbit Polyclonal against HK1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
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