Search results for ZAP70 antibody

Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody, Abbexa, abx001807

ZAP70 Antibody is a Rabbit Polyclonal antibody against ZAP70. This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody, Abbexa, abx239583

ZAP70 Antibody is a Rabbit Polyclonal against ZAP70.

Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody, Abbexa, abx239582

ZAP70 Antibody is a Rabbit Polyclonal against ZAP70.

Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody, Abbexa, abx036841

Rabbit Polyclonal against the ZAP70 protein.

Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody, Abbexa, abx016023

ZAP70 (zeta-chain associated protein kinase), a 70 kDa member of the SYK tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders.ZAP70 controls TCR (T-cell antigen receptor)-linked signal transduction pathways.Its key role in thymocytes development and mature T lymphocytes activation has been illustrated by the characterization of several human immunodeficiencies presenting with mutations in the ZAP70 gene.ZAP70 is also expressed in several types of B-cell neoplasm and is easily detected by immunohistochemistry, providing a useful prognostic marker in patients with chronic lymphocytic leukaemia.

Tyrosine-protein kinase ZAP-70 (ZAP70) Antibody, Abbexa, abx344861

Tyrosine-protein kinase ZAP-70 (ZAP70) Antibody is a Rabbit Polyclonal antibody for the detection of Mouse, Human Zap70.

PE anti-ZAP70 Antibody anti-ZAP70 - A15114B, BioLegend, 691203

PE anti-ZAP70 Antibody anti-ZAP70 - A15114B, BioLegend, 691204

Purified anti-ZAP70 Antibody anti-ZAP70 - A15114B, BioLegend, 691202

Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody, Abbexa, abx025459

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. This antibody is supplied as crude ascites.