Search results for 3725

Transcription Factor Jun (JUN) Antibody, Abbexa, abx402475

Transcription Factor Jun (JUN) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human JUN.

c-Jun (pS63) Antibody, Abbexa, abx000133

c-Jun (pS63) Antibody is a Rabbit Polyclonal antibody against c-Jun (pS63). c-Jun is a member of the Jun Family containing c-Jun, JunB and JunD, and is a component of the transcription factor AP-1 (activator protein-1). AP-1 is composed of dimers of Fos, Jun and ATF family members and binds to and activates transcription at TRE/AP-1 elements (reviewed in 1). Extracellular signals including growth factors, chemokines and stress activate AP-1-dependent transcription. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73 through SAPK/JNK (reviewed in 2). Knock-out studies in mice have shown that c-Jun is essential for embryogenesis (3), and subsequent studies have demonstrated roles for c-Jun in various tissues and developmental processes including axon regeneration (4), liver regeneration (5) and T cell development (6). AP-1 regulated genes exert diverse biological functions including cell proliferation, differentiation, and apoptosis, as well as transformation, invasion and metastasis, depending on cell type and context (7-9). Other target genes regulate survival as well as hypoxia and angiogenesis (8,10). c-Jun has emerged as a promising therapeutic target for cancer, vascular remodeling, acute inflammation, as well as rheumatoid arthritis (11,12).

Transcription Factor Jun Phospho-Tyr170 (JUN pY170) Antibody, Abbexa, abx333477

Jun (pY170) Antibody is a Rabbit Polyclonal against Jun (pY170).

Human Transcription Factor Jun (JUN) ELISA Kit, Abbexa, abx051285

Human Transcription Factor Jun (JUN) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Transcription Factor Jun (JUN) concentrations in serum, plasma and other biological fluids.

Transcription Factor Jun (JUN) Antibody (FITC), Abbexa, abx337991

Transcription Factor Jun (JUN) Antibody (FITC) is a Rabbit Polyclonal against Transcription Factor Jun (JUN).

c-Jun antibody, Genetex, GTX112974

c-Jun Antibody (YA3657), MedChemexpress, HY-P83960

c-Jun Antibody (YA3657) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to c-Jun.

JUN (pS73) Antibody, Abbexa, abx000171

JUN (pS73) Antibody is a Rabbit Polyclonal antibody against JUN (pS73). This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.

Transcription Factor Jun Phospho-Thr231 (JUN pT231) Antibody, Abbexa, abx326705

Jun (pT231) Antibody is a Rabbit Polyclonal against Jun (pT231).

Transcription Factor Jun Phospho-Tyr170 (JUN pY170) Antibody, Abbexa, abx328444

Jun (pY170) Antibody is a Rabbit Polyclonal against Jun (pY170).