Search results for Hexokinase

Hexokinase-4 (GCK) Antibody, Abbexa, abx321463

GCK Antibody is a Rabbit Polyclonal against GCK.

Hexokinase 2 (HK2) Antibody, Abbexa, abx011658

The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases.Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Hexokinase-1 (HK1) Antibody, Abbexa, abx274888

This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Hexokinase-1 (HK1) Antibody is a Rabbit Polyclonal against Mouse HK1.

Hexokinase-4 (GCK) Antibody, Abbexa, abx033752

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of the gene for GCK results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in the gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), also called maturity onset diabetes of the young, type 2 (MODY2) ; mutations have also been associated with persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

Hexokinase I Antibody (YA739), MedChemexpress, HY-P80702

Hexokinase I Antibody (YA739) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Hexokinase I.

Hexokinase II Antibody (YA386), MedChemexpress, HY-P80703

Hexokinase II Antibody (YA386) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hexokinase II.

Hexokinase 3 (HK3) Antibody, Abbexa, abx033898

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).

Hexokinase-1 (HK1) Antibody, Abbexa, abx100798

Polyclonal Antibody to Hexokinase-1 (HK1).

Hexokinase II antibody [HL2001], Genetex, GTX637902

Hexokinase-1 (HXK1) Antibody, Abbexa, abx013419

Rabbit polyclonal antibody against HXK1 protein. Immunogen region is N-terminal.