Search results for IGF1R

IGF1R / INSR (pY1161) Antibody, Abbexa, abx329493

IGF1R/INSR (pY1161) Antibody is a Rabbit Polyclonal against IGF1R/INSR (pY1161).

IGF1R beta antibody [HL1957], Genetex, GTX637794

IGF1R beta antibody [HL1958], Genetex, GTX637795

IGF1R / INSR (pY1161) Antibody, Abbexa, abx329710

IGF1R/INSR (pY1161) Antibody is a Rabbit Polyclonal against IGF1R/INSR (pY1161).

IGF1R beta antibody [3C8B1], Genetex, GTX83067

Anti-IGF1R (extracellular) Antibody, Alomone Labs, ANT-045

Anti-IGF1R (extracellular) Antibody(#ANT-045) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, immunohistochemistry, and live cell flow cytometry applications. It has been designed to recognize IGF1R from mouse, rat, and human samples. Anti-IGF1R (extracellular) Antibody –(Carrier Free) (#ANT-045-CF) is a highly specific antibody directed against an epitope of the rat protein. This ready-to-use, carrier-free formulation is free of BSA and sodium azide, making it ideal for conjugation, sensitive downstream applications and specialized assay development. The size of this version is0.2 mlat a concentration of1 mg/ml. It has been designed to recognize IGF1R from mouse, rat, and human samples. Carrier Free: Anti-IGF1R (extracellular) Antibody –(Carrier Free) (#ANT-045-CF) is a highly specific antibody directed against an epitope of the rat protein. This ready-to-use, carrier-free formulation is free of BSA and sodium azide, making it ideal for conjugation, sensitive downstream applications and specialized assay development. The size of this version is0.2 mlat a concentration of1 mg/ml. It has been designed to recognize IGF1R from mouse, rat, and human samples.

Anti-IGF1R (extracellular) Antibody, Alomone Labs, ANT-045-CF

Anti-IGF1R (extracellular) Antibody(#ANT-045) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, immunohistochemistry, and live cell flow cytometry applications. It has been designed to recognize IGF1R from mouse, rat, and human samples. Anti-IGF1R (extracellular) Antibody –(Carrier Free) (#ANT-045-CF) is a highly specific antibody directed against an epitope of the rat protein. This ready-to-use, carrier-free formulation is free of BSA and sodium azide, making it ideal for conjugation, sensitive downstream applications and specialized assay development. The size of this version is0.2 mlat a concentration of1 mg/ml. It has been designed to recognize IGF1R from mouse, rat, and human samples. Carrier Free: Anti-IGF1R (extracellular) Antibody –(Carrier Free) (#ANT-045-CF) is a highly specific antibody directed against an epitope of the rat protein. This ready-to-use, carrier-free formulation is free of BSA and sodium azide, making it ideal for conjugation, sensitive downstream applications and specialized assay development. The size of this version is0.2 mlat a concentration of1 mg/ml. It has been designed to recognize IGF1R from mouse, rat, and human samples.

IGF1R-Beta Primary Antibody, ProMab, 20138

IGF1R (insulin-like growth factor 1 receptor), a transmembrane receptor tyrosine kinase, is widely expressed in many cell types within fetal and postnatal tissues, and in many cell lines. Upon binding to its ligands, IGF-I and IGF-II, receptor autophosphorylation occurs. The triple tyrosine cluster within the kinase domain (Tyr1131, Tyr1135 and Tyr1136) is the earliest major site of autophosphorylation. Phosphorylation of these three tyrosine residues is necessary for kinase activation.Insulin receptors (IRs) share significant similarity with IGF1 receptors in both structure and function,including an equivalent triple tyrosine cluster within the activation loop of the kinase domain (Tyr1146, Tyr1150 and Tyr1151).Tyrosine autophosphorylation of insulin receptor is one of the earliest cellular responses to insulin stimulation. Autophosphorylation begins with phosphorylation of Tyr1146 and either Tyr1150 or Tyr1151. Full kinase activation requires the triple tyrosine phosphorylation.

IGF1R-Beta Primary Antibody, ProMab, 20149

IGF1R(insulin-like growth factor 1 receptor), a transmembrane receptor tyrosine kinase, is widely expressed in many cell types within fetal and postnatal tissues, and in many cell lines. Upon binding to its ligands, IGF-I and IGF-II, receptor autophosphorylation occurs. The triple tyrosine cluster within the kinase domain (Tyr1131, Tyr1135 and Tyr1136) is the earliest major site of autophosphorylation. Phosphorylation of these three tyrosine residues is necessary for kinase activation.Insulin receptors (IRs) share significant similarity with IGF1 receptors in both structure and function,including an equivalent triple tyrosine cluster within the activation loop of the kinase domain (Tyr1146, Tyr1150 and Tyr1151).Tyrosine autophosphorylation of insulin receptor is one of the earliest cellular responses to insulin stimulation. Autophosphorylation begins with phosphorylation of Tyr1146 and either Tyr1150 or Tyr1151. Full kinase activation requires the triple tyrosine phosphorylation.

Mouse Monoclonal Antibody to IGF1R, ProMab, 32052

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.