Search results for ER

ER-MP58 Antibody, Abbexa, abx414120

ER-MP58 Antibody is a Rat Monoclonal antibody against ER-MP58.

ER-MP58 Antibody, Abbexa, abx414119

ER-MP58 Antibody is a Rat Monoclonal antibody against ER-MP58.

ER-TR7 Antibody, Abbexa, abx414135

ER-TR7 Antibody is a Rat Monoclonal antibody against ER-TR7.

ER Primary Antibody, ProMab, 20139

ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites. Serines 104, 106, 118 and 167 are located in the amino-terminal transcription activation function domain AF-1, and phosphorylation of these serines plays an important role in regulating ER activity. Ser118 may be the substrate of the transcription regulatory kinase cdK7. Ser167 may be phosphorylated by p90RSK and Akt. Phosphorylation of Ser167 may confer tamoxifen resistance in breast cancer patients.

ER Alpha (ESR1) Antibody, Abbexa, abx011649

The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ER mRNA transcripts, which differ primarily in their 5-prime untranslated regions. Two isoforms of the human ER, ERA and ER beta, occur, each with distinct tissue and cell patterns of expression. Pelletier and El-Alfy (2000) studied the immunocytochemical localization of ESRA and ESRB in human reproductive tissues. In the ovary, ERB immunoreactivity was found in nuclei of granulosa cells of growing follicles at all stages from primary to mature follicles, interstitial gland, and germinal epithelium cells. Nuclear staining for ERA occurred in thecal, interstitial gland, and germinal epithelium cells. In the uterus, strong ERA immunoreactivity was detected in nuclei of epithelial, stromal, and muscle cells.

Anti-ER (Estrogen receptor), DB Biotech, DB 053-0.1

Anti-ER (Estrogen receptor), DB Biotech, DB 053-0.2

Anti-ER (Estrogen receptor), DB Biotech, DB 053-0.5

Anti-ER (Estrogen receptor), DB Biotech, DB 053-1

Anti-ER (Estrogen receptor), DB Biotech, DB 053-RTU-7