Search results for FAK

Focal Adhesion Kinase (FAK) Antibody, Abbexa, abx403438

Human Focal Adhesion Kinase (FAK) Antibody is a Mouse monoclonal against Focal Adhesion Kinase (FAK).

Phospho-FAK (Tyr397) Antibody (YA198), MedChemexpress, HY-P80460

Phospho-FAK (Tyr397) Antibody (YA198) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-FAK (Tyr397).

Anti-FAK (Phospho-Tyr861) Antibody, Covalab, Ref 00123821

Anti-FAK (phospho S732) antibody, Abcam, AB4792

Focal Adhesion Kinase is a 125 kDa non-receptor protein tyrosine kinase that plays a key role in signalling by growth factors, extracellular matrix and stress signals. Indeed, Focal Adhesion Kinase plays a central role in cell spreading, differentiation, migration, cell death and acceleration of the G1 to S phase transition of the cell cycle. Cyclin-dependent kinase-5 (Cdk5), a serine/threonine kinase and an important regulator in brain development, has been found to be essential for phosphorylation at serine 732. In the context of the Focal Adhesion Kinase-Related Non-Kinase (FRNK), the c-terminal non-kinase domain of Focal Adhesion Kinase that acts as a dominant negative inhibitor of Focal Adhesion Kinase signalling, other serine kinases appear to readily phosphorylate this same site. The functional significance of phosphorylation on serine 732 is yet to be determined.

Anti-FAK (phospho S910) antibody, Abcam, AB4794

FAK is a non-receptor protein tyrosine kinase discovered as a substrate for Src and it is a key protein in integrin, growth factor and bioactive peptide signaling. FAK plays a central role in cell spreading, differentiation, migration, cell death and acceleration of the G1 to S phase transition of the cell cycle. FAK regulation includes phosphorylation at multiple tyrosine and serine residues. Phosphorylation of tyrosine generally is associated with positive regulation and growth promotion, however, dephosphorylation at these sites occurs as cells enter mitosis (M-Phase of the cell cycle). In contrast, serine phosphorylation either remains high or is increased as cells enter mitosis and may play a role in focal adhesion disassembly.

Anti-FAK (phospho Y407) antibody, Abcam, AB4814

Focal Adhesion Kinase is a non-receptor protein tyrosine kinase discovered as a substrate for Src and as a key element of integrin signalling. Focal Adhesion Kinase plays a central role in cell spreading, differentiation, migration, cell death and acceleration of the G1 to S phase transition of the cell cycle. The activity of the phosphorylation site pTyr407 is currently unknown.

Anti-FAK (phospho Y576) antibody, Abcam, AB226847

Anti-FAK (phospho Y861) antibody, Abcam, AB4804

Focal Adhesion Kinase is a 125 kDa non-receptor protein tyrosine kinase that is a substrate for Src and a key element in growth factor and integrin signalling. Focal Adhesion Kinase plays a central role in cell spreading, differentiation, migration, cell death and acceleration of the G1 to S phase transition of the cell cycle. Tyr861 of Focal Adhesion Kinase is a major Src phosphorylation site that allows Focal Adhesion Kinase to bind to integrins and is also involved in cancer.

Anti-FAK (phospho Y925) antibody, Abcam, AB38512

Focal Adhesion Kinase (FAK) Antibody, Abbexa, abx176482

Focal Adhesion Kinase (FAK) Antibody is a Rabbit Polyclonal antibody against Focal Adhesion Kinase (FAK).