Search results for H4
APC anti-human B7-H4 Antibody anti-B7-H4 - MIH43, BioLegend, 358107
Additional reported applications (for the relevant formats) includes immunofluorescence2.
Host
Mouse
Reactivity
Human
Applications
FC - Quality tested
Conjugation
APC anti-human B7-H4 Antibody anti-B7-H4 - MIH43, BioLegend, 358108
Additional reported applications (for the relevant formats) includes immunofluorescence2.
Host
Mouse
Reactivity
Human
Applications
FC - Quality tested
Conjugation
APCFire 750 anti-human B7-H4 Antibody, B7-H4, MIH43, BioLegend, 358117
Additional reported applications (for the relevant formats) includes immunofluorescence2.
Host
Mouse
Reactivity
Human
Applications
FC -Quality tested
Conjugation
APCFire 750 anti-human B7-H4 Antibody, B7-H4, MIH43, BioLegend, 358118
Additional reported applications (for the relevant formats) includes immunofluorescence2.
Host
Mouse
Reactivity
Human
Applications
FC -Quality tested
Conjugation
PE anti-human B7-H4 Antibody anti-B7-H4 - MIH43, BioLegend, 358103
Additional reported applications (for the relevant formats) includes immunofluorescence2.
Host
Mouse
Reactivity
Human
Applications
FC - Quality tested
Conjugation
PE anti-human B7-H4 Antibody anti-B7-H4 - MIH43, BioLegend, 358104
Additional reported applications (for the relevant formats) includes immunofluorescence2.
Host
Mouse
Reactivity
Human
Applications
FC - Quality tested
Conjugation
Purified anti-human B7-H4 Antibody anti-B7-H4 - MIH43, BioLegend, 358101
Additional reported applications (for the relevant formats) includes immunofluorescence2.
Host
Mouse
Reactivity
Human
Applications
FC -Quality testedIHC-F, ICC -Reported in the literature, not verified in house
Conjugation
Purified anti-human B7-H4 Antibody anti-B7-H4 - MIH43, BioLegend, 358102
Additional reported applications (for the relevant formats) includes immunofluorescence2.
Host
Mouse
Reactivity
Human
Applications
FC -Quality testedIHC-F, ICC -Reported in the literature, not verified in house
Conjugation
Properdin, Mouse, mAb H4, Hycult Biotech, HM1139
Monoclonal antibody H4 recognizes mouse properdin. The complement system is the first line of defense against pathogens and facilitates elimination of apoptotic and damaged cells. Positive regulator plasma protein properdin is critical for the alternative pathway of complement. It is a single-chain glycoprotein (ca 53kDa) consisting of six TSR sequences. In the blood it exists as a mixture of preferably head-to-tail trimers, but also dimers and tetramers. The protein is produced by leukocytes, like activated neutrophils monocytes and T-lymphocytes, but also by eg. stressed endothelial cells. Properdin can both initiate and positively regulate the alternative pathway activity together with C3 and factors B, D, I and H. It binds to C3b where It stabilizes the labile C3bBb convertase which is deposited on immune complexes or foreign surfaces. Thereby enhancing the AP by stimulation of amplification of C3bBb-convertase formation in competition with catabolism of C3b by factor I, which uses factor H as a cofactor. The local amplification process leads to the creation of the alternative pathway C5 convertase, C3bBb3b, and initiates the terminal pathway of complement activation. The alternative pathway may account for ca 80% of the terminal pathway activity. Properdin has also been shown to directly limit factor H activity. Recent studies show that properdin is also a pattern-recognition receptor (PRR) able to bind directly to microbial surfaces, apoptotic and necrotic cells (dangerous nonself and altered self). Inappropriate activation or dysregulation of the alternative pathway is a critical factor in development of several autoimmune conditions. Targets opsonized with properdin are labeled for clearance by scavenger cells, even without complement. This makes it a potential therapeutic target in diseases. Recent studies has shown renewed interest in the evaluating role of properdin in disease pathogenesis, like Asthma, arthritis, septic shock, AMD and C3 glomerulopathy.
Host
Mouse
Reactivity
Applications
Conjugation
Histone H4 (HIST1H4A) Antibody, Abbexa, abx318696
HIST1H4A Antibody is a Rabbit Polyclonal against HIST1H4A.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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