Search results for Pyruvate Dehydrogenase

Pyruvate Dehydrogenase Complex Component X (PDHX) Antibody, Abbexa, abx031492

PDX1, located in the mitochondrial matrix, is required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. Eukaryotic pyruvate dehydrogenase complexes are organized about a core consisting of the oligomeric dihydrolipoamide acetyl-transferase, around which are arranged multiple copies of pyruvate dehydrogenase, dihydrolipoamide dehydrogenase and protein X bound by noncovalent bonds. Defects in PDHX are a cause of lacticacidemia. PDX1 belongs to the 2-oxoacid dehydrogenase family and contains 1 lipoyl-binding domain.

Pyruvate Dehydrogenase Kinase Isozyme 4 (PDK4) Antibody, Abbexa, abx002212

PDK4 Antibody is a Rabbit Polyclonal antibody against PDK4. This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

Pyruvate Dehydrogenase Kinase Isozyme 2 (PDK2) Antibody, Abbexa, abx033136

PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

Pyruvate Dehydrogenase Kinase Isozyme 4 (PDK4) Antibody, Abbexa, abx313333

PDK4 Antibody is a Rabbit Polyclonal against PDK4.

Pyruvate Dehydrogenase Kinase Isozyme 3 (PDK3) Antibody, Abbexa, abx375686

Pyruvate Dehydrogenase Kinase Isozyme 3 (PDK3) Antibody is a Rabbit Polyclonal antibody against Pyruvate Dehydrogenase Kinase Isozyme 3 (PDK3).

Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) Antibody, Abbexa, abx104079

Polyclonal Antibody to Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1).

Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) Antibody, Abbexa, abx147623

Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) Antibody is a Rabbit Polyclonal antibody for the detection of PDK1. Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.

Pyruvate Dehydrogenase Kinase Isozyme 2 (PDK2) Antibody, Abbexa, abx328656

PDK2 Antibody is a Rabbit Polyclonal against PDK2.

Pyruvate dehydrogenase kinase 1 / PDK1 antibody [N1C3], Genetex, GTX105999

Pyruvate Dehydrogenase Kinase Isozyme 4 (PDK4) Antibody, Abbexa, abx033140

PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.