Search results for db

Bcl2-Associated Agonist of Cell Death Phospho-Ser124 (BAD pS124) Antibody, Abbexa, abx032135

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq].

Alpha Synuclein (SNCA) Antibody (APC), Abbexa, abx442807

Alpha Synuclein Antibody is a Mouse Monoclonal against Alpha Synuclein.

CHK1 (pS317) Antibody, Abbexa, abx031852

Checkpoint pathways control the order and timing of cell cycle transitions and ensure that critical events, such as DNA replication and chromosome segregation, are completed with high fidelity. The S. pombe Chk1 gene encodes a protein kinase that is required for the DNA damage checkpoint. Antibodies against CHK1 recognized a 54-kD protein on immunoblots of mammalian cell extracts. However, CHK1 is modified in response to DNA damage. In vitro, CHK1 directly phosphorylated a regulator of CDC2 tyrosine phosphorylation, CDC25C. In response to DNA damage, CHK1 phosphorylates and inhibits CDC25C, thus preventing activation of the CDC2-cyclin B complex and mitotic entry. CHK1 directly phosphorylates CDC25A during an unperturbed cell cycle, and that phosphorylation of CDC25A by CHK1 is required for cells to delay cell cycle progression in response to double-strand DNA breaks.

Alpha Synuclein (SNCA) Antibody (Biotin), Abbexa, abx443088

Alpha Synuclein Antibody is a Mouse Monoclonal against Alpha Synuclein.

STAT5a (pS726) Antibody, Abbexa, abx031921

STAT5a is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this protein is found to induce the expression of BCL2L1/BCL-X (L), which suggests the antiapoptotic function of this protein in cells.

Alpha Synuclein (SNCA) Antibody (ATTO594), Abbexa, abx441122

Alpha Synuclein Antibody is a Mouse Monoclonal against Alpha Synuclein.

RSV Nucleoprotein Antibody, Abbexa, abx022186

RSV Nucleoprotein Antibody is a Mouse monoclonal antibody for the detection of Respiratory Syncytial Virus Nucleoprotein (RSV N).

Myocyte-Specific Enhancer Factor 2C Phospho-Thr300 (MEF2C pT300) Antibody, Abbexa, abx031964

MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. This protein controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It may also be involved in neurogenesis and in the development of cortical architecture.

Anti-Human HTT Nanobody (SAA1178), AntibodySystem, RHE38301

Anti-RABV G/Glycoprotein Antibody (50AD1), AntibodySystem, RVV03908