Search results for receptor for antibody

Estrogen Receptor alpha antibody, Genetex, GTX31883

IL17 Receptor E antibody, Genetex, GTX32106

Adiponectin Receptor 1 antibody, Genetex, GTX32425

IL1 Receptor antagonist antibody, Genetex, GTX32673

PDGF Receptor beta antibody, Genetex, GTX32777

Insulin Receptor (INSR) Antibody, Abbexa, abx033580

INSR is a receptor that binds insulin and has a tyrosine-protein kinase activity. Autophosphorylation activates the kinase activity. This Type I mebrane protein is composed of a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. After being transported from the endoplasmic reticulum to the Golgi apparatus, the single glycosylated precursor is further glycosylated and then cleaved, followed by its transport to the plasma membrane. Defects in INSR are the cause of insulin resistance of various forms, including mild insulin-resistant diabetes mellitus with acanthosis nigricans, minor physical abnormalities and sometimes polycystic ovaries. Insulin resistance associated with acanthosis nigricans, hirsutism and hyperandrogenism is referred to as insulin resistance type A. Defects in INSR are the cause of Rabson-Mendenhall syndrome, also known as Mendenhall syndrome. It is a severe insulin resistance syndrome characterized by insulin-resistant diabetes mellitus with pineal hyperplasia and somatic abnormalities. Typical features include coarse, senile-appearing facies, dental and skin abnormalities, abdominal distension, and phallic enlargement. Inheritance is autosomal recessive. Defects in INSR are the cause of leprechaunism, also known as Donohue syndrome. Leprechaunism represents the most severe form of insulin resistance syndrome, characterized by intrauterine and postnatal growth retardation and death in early infancy. Inheritance is autosomal recessive. Defects in INSR may be associated with noninsulin-dependent diabetes mellitus.

Prolactin Receptor (PRLR) Antibody, Abbexa, abx126414

PRLR Antibody is a Rabbit Polyclonal against PRLR.

Progesterone Receptor (PGR) Antibody, Abbexa, abx326788

PGR Antibody is a Rabbit Polyclonal against PGR.

Progesterone Receptor (PGR) Antibody, Abbexa, abx159642

PGR Antibody is a Mouse Monoclonal against PGR.

Glucagon Receptor (GCGR) Antibody, Abbexa, abx034152

This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.