Search results for 7124

Tumor Necrosis Factor (TNF) Antibody, Abbexa, abx117001

TNF Antibody is a Rabbit Polyclonal antibody against TNF. TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane proteinMembrane-bound TNF-α is cleaved by the metalloprotease TACE/ADAM17 to geneRate a soluble homotrimerBoth membrane and soluble forms of TNF-α are biologically activeTNF-α is produced by a variety of immune cells including T cells, B cells, NK cells, and macrophagesCellular response to TNF-α is mediated through interaction with receptors TNF-R1 and TNF-R2 and results in activation of pathways that favor both cell survival and apoptosis depending on the cell type and biological contextActivation of kinase pathways (including JNK, Erk (p44/42), p38 MAPK, and NF-κB) promotes the survival of cells, while TNF-α-mediated activation of caspase-8 leads to programmed cell deathTNF-α plays a key regulatory role in inflammation and host defense against bacterial infection, notably Mycobacterium tuberculosisThe role of TNF-α in autoimmunity is underscored by blocking TNF-α action to treat rheumatoid arthritis and Crohn’s diseaseThis protein is involved in Immunology.

TNF alpha antibody, Genetex, GTX10949

TNF alpha antibody, Genetex, GTX110520

TNF alpha antibody, Genetex, GTX26671

TNF alpha antibody, Genetex, GTX27742

TNF alpha antibody [2C8], Genetex, GTX28348

TNF alpha antibody [F6C5], Genetex, GTX28349

Tumor Necrosis Factor (TNF) Antibody, Abbexa, abx415721

Tumor Necrosis Factor (TNF) Antibody is a Mouse Monoclonal antibody against Tumor Necrosis Factor (TNF).

Tumor Necrosis Factor (TNF) Antibody, Abbexa, abx000662

TNF Antibody is a Rabbit Polyclonal antibody against TNF. This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Tumor Necrosis Factor (TNF) Antibody (FITC), Abbexa, abx107435

Tumor necrosis factor Antibody (FITC) is a Rabbit Polyclonal antibody against Tumor necrosis factor conjugated to FITC.