Search results for GP

PE Anti-CD42a/GP-IX antibody [GR-P], Abcam, AB30399

Pre-Glycoprotein Polyprotein GP Complex (GPC) Antibody (HRP), Abbexa, abx319922

GPC Antibody (HRP) is a Rabbit Polyclonal against GPC conjugated to HRP.

CF405M Anti-CD42a/GP-IX antibody [GR-P], Abcam, AB119483

CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye ® , BD Horizon™ V450.

Anti-MARV Envelope glycoprotein (GP) Human IgA ELISA Kit, ProteoGenix, KPTX440

Description of Anti-MARV Envelope glycoprotein (GP) Human IgA ELISA Kit Introduction The Anti-MARV Envelope glycoprotein (GP) Human IgA ELISA Kit is a highly sensitive and specific tool used for the detection and quantification of IgA antibodies against the envelope glycoprotein of the Marburg virus (MARV). This kit is designed for research use and is not intended for diagnostic purposes. In this article, we will discuss the structure, activity, and potential applications of this kit as a therapeutic target in the fight against MARV. Structure of Anti-MARV Envelope glycoprotein (GP) Human IgA ELISA Kit The Anti-MARV Envelope glycoprotein (GP) Human IgA ELISA Kit is composed of several components, including a microplate coated with MARV envelope glycoprotein, a standard solution, and a detection antibody. The microplate is coated with the MARV envelope glycoprotein, which is the target antigen for the IgA antibodies. The standard solution contains known concentrations of IgA antibodies against the MARV envelope glycoprotein, which are used to create a standard curve for quantification. The detection antibody is labeled with an enzyme, which produces a colorimetric signal when it binds to the IgA antibodies present in the sample. Activity of Anti-MARV Envelope glycoprotein (GP) Human IgA ELISA Kit The Anti-MARV Envelope glycoprotein (GP) Human IgA ELISA Kit utilizes the principle of enzyme-linked immunosorbent assay (ELISA) to detect and quantify IgA antibodies against the MARV envelope glycoprotein. The microplate coated with the MARV envelope glycoprotein is first incubated with the sample, allowing any IgA antibodies present in the sample to bind to the antigen. After washing away any unbound components, the detection antibody is added, which binds to the IgA antibodies bound to the antigen. Finally, a substrate solution is added, which is converted by the enzyme on the detection antibody into a colored product. The intensity of the color is directly proportional to the amount of IgA antibodies present in the sample, allowing for the quantification of these antibodies. Applications of Anti-MARV Envelope glycoprotein (GP) Human IgA ELISA Kit The Anti-MARV Envelope glycoprotein (GP) Human IgA ELISA Kit has a wide range of potential applications, including as a therapeutic target for the development of treatments against MARV. The detection and quantification of IgA antibodies against the MARV envelope glycoprotein can provide valuable insights into the immune response of individuals infected with MARV. This information can be used to identify potential targets for therapeutic interventions and to monitor the efficacy of treatments. Additionally, this kit can be used in research studies to investigate the prevalence and dynamics of IgA antibodies against the MARV envelope glycoprotein in different populations. This information can aid in the development of strategies for the prevention and control of MARV outbreaks. Furthermore, the Anti-MARV Envelope glycoprotein (GP) Human IgA ELISA Kit can be used in the development and evaluation of vaccines against MARV. By measuring the levels of IgA antibodies against the MARV envelope glycoprotein in vaccinated individuals, researchers can assess the effectiveness of the vaccine in inducing an immune response and potentially predict its protective efficacy. Conclusion The Anti-MARV Envelope glycoprotein (GP) Human IgA ELISA Kit is a valuable tool for the detection and quantification of IgA antibodies against the MARV envelope glycoprotein. Its structure and activity make it a highly sensitive and specific assay, with a wide range of potential applications in research and as a therapeutic target in the fight against MARV. Further studies and developments utilizing this kit can contribute to the understanding and control of MARV outbreaks and the development of effective treatments and vaccines.

Anti-MARV Envelope glycoprotein (GP) Human IgG ELISA Kit, ProteoGenix, KPTX438

Description of Anti-MARV Envelope glycoprotein (GP) Human IgG ELISA Kit Understanding the Structure and Function of Anti-MARV Envelope Glycoprotein (GP) Human IgG ELISA Kit Introduction The Ebola virus is a highly infectious and deadly pathogen that has caused numerous outbreaks in Africa. One of the most virulent strains of Ebola is the Marburg virus (MARV), which shares similar characteristics and symptoms with Ebola. Due to the high mortality rate and lack of effective treatments, there is a critical need for therapeutics and diagnostic tools to combat MARV. The Anti-MARV Envelope glycoprotein (GP) Human IgG ELISA Kit is a valuable research tool that aids in the detection and characterization of MARV infection. In this article, we will delve into the structure, activity, and application of this kit in the field of MARV research. Structure of Anti-MARV GP Human IgG ELISA Kit The Anti-MARV GP Human IgG ELISA Kit is a sandwich enzyme-linked immunosorbent assay (ELISA) that detects the presence of IgG antibodies specific to the envelope glycoprotein of MARV. The kit contains pre-coated microplates with MARV GP antigen, horseradish peroxidase (HRP)-conjugated anti-human IgG antibodies, and all necessary reagents for the assay. The microplate wells are coated with a monoclonal antibody that specifically binds to the MARV GP antigen, while the HRP-conjugated antibodies bind to the IgG antibodies present in the sample. The kit also includes a standard curve for quantification of IgG levels in the sample. Activity of Anti-MARV GP Human IgG ELISA Kit The Anti-MARV GP Human IgG ELISA Kit is a highly sensitive and specific tool for the detection of IgG antibodies against MARV GP. The assay follows a simple and rapid protocol, making it suitable for high-throughput screening. The samples, along with the standard curve, are added to the coated microplate wells and incubated. The IgG antibodies present in the sample bind to the MARV GP antigen, while the excess antibodies are washed away. The HRP-conjugated antibodies are then added, and a colorimetric substrate is used to visualize the bound antibodies. The intensity of the color is directly proportional to the amount of IgG antibodies present in the sample, which can be quantified using a microplate reader. Application of Anti-MARV GP Human IgG ELISA Kit The Anti-MARV GP Human IgG ELISA Kit has several applications in the field of MARV research. It is primarily used for the detection and quantification of IgG antibodies in serum or plasma samples from individuals who have been exposed to MARV or have received a vaccine against it. The kit can also be used to monitor the immune response to MARV infection or vaccination. Furthermore, it can aid in the identification of potential therapeutic targets by detecting the presence of IgG antibodies against specific epitopes on the MARV GP antigen. The kit can also be used to study the kinetics of the immune response and to evaluate the efficacy of potential treatments or vaccines in preclinical studies. Conclusion In summary, the Anti-MARV GP Human IgG ELISA Kit is a valuable tool for the detection and characterization of MARV infection. Its simple and rapid protocol, along with its high sensitivity and specificity, make it an ideal choice for researchers studying MARV. The kit has numerous applications in both diagnostic and research settings, making it an essential tool in the fight against this deadly virus.

Anti-MARV Envelope glycoprotein (GP) Human IgM ELISA Kit, ProteoGenix, KPTX439

Description of Anti-MARV Envelope glycoprotein (GP) Human IgM ELISA Kit Introduction The Anti-MARV Envelope glycoprotein (GP) Human IgM ELISA Kit is a powerful tool for detecting and quantifying IgM antibodies against the Envelope glycoprotein (GP) of the Marburg virus (MARV) in human serum or plasma samples. MARV is a highly infectious and deadly virus that belongs to the Filoviridae family, along with the Ebola virus. Outbreaks of MARV have been reported in Africa, with a mortality rate of up to 90%. Therefore, the development of effective diagnostic tools and therapeutic strategies is crucial for controlling and treating MARV infections. Structure of Anti-MARV GP Human IgM ELISA Kit The Anti-MARV GP Human IgM ELISA Kit is a sandwich enzyme-linked immunosorbent assay (ELISA) that utilizes the principle of antigen-antibody interaction for the detection of IgM antibodies against MARV GP. The kit contains pre-coated 96-well microplates, which are coated with recombinant MARV GP antigen. The kit also includes a conjugate, which is a horseradish peroxidase (HRP)-labeled anti-human IgM antibody, and a chromogenic substrate, which is tetramethylbenzidine (TMB). The kit also includes a stop solution to terminate the enzyme reaction. Activity of Anti-MARV GP Human IgM ELISA Kit The Anti-MARV GP Human IgM ELISA Kit works by first binding the IgM antibodies present in the sample to the pre-coated MARV GP antigen on the microplate. After washing away any unbound components, the HRP-conjugated anti-human IgM antibody is added, which binds to the IgM antibodies that are already bound to the MARV GP antigen. The addition of the chromogenic substrate, TMB, triggers a color change in the presence of the HRP enzyme, indicating the presence of IgM antibodies against MARV GP in the sample. The intensity of the color is directly proportional to the amount of IgM antibodies present in the sample. Application of Anti-MARV GP Human IgM ELISA Kit The Anti-MARV GP Human IgM ELISA Kit has several applications in the field of MARV research and diagnosis. One of its main uses is in the detection and monitoring of MARV infections. IgM antibodies against MARV GP are produced in the early stages of infection and can be detected within a few days of symptom onset. Therefore, the Anti-MARV GP Human IgM ELISA Kit can be used for early diagnosis and monitoring of MARV infections, allowing for prompt treatment and control of outbreaks. The kit can also be used for serological surveys and epidemiological studies to determine the prevalence of MARV infections in a population. This information is crucial for understanding the distribution and transmission of the virus and for implementing preventive measures. Furthermore, the Anti-MARV GP Human IgM ELISA Kit can be used in the development and evaluation of potential therapeutics and vaccines against MARV. The kit can be used to measure the levels of IgM antibodies in response to these interventions, providing valuable information on their effectiveness. Therapeutic Target The Envelope glycoprotein (GP) of MARV is a potential therapeutic target as it plays a crucial role in viral entry and pathogenesis. The Anti-MARV GP Human IgM ELISA Kit can aid in the identification and characterization of novel therapeutic agents that target MARV GP and inhibit its function. Research Use The Anti-MARV GP Human IgM ELISA Kit is a valuable tool for researchers studying the pathogenesis of MARV and developing strategies for its control and treatment. The kit can also be used in the development of new diagnostic tests and in the evaluation of potential antiviral drugs and vaccines. Conclusion In summary, the Anti-MARV GP Human IgM ELISA Kit is a highly sensitive and specific tool for the detection

Anti-CD42a/GP-IX antibody [EP5294] - BSA and Azide free, Abcam, AB284806

ab284806 is the carrier-free version of ab133573 The production method for this product has been changed from hybridoma to recombinant on 18th June 2024. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.

Anti-CD42a/GP-IX antibody [EPR5295] - BSA and Azide free, Abcam, AB247625

ab247625 is the carrier-free version of ab108304 . Species reactivity Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.

Ebola Virus Glycoprotein Receptor-Binding Domain (EBOV GP RBD) Antibody, Abbexa, abx201324

Ebola Virus Glycoprotein Receptor-Binding Domain (EBOV GP RBD) Antibody (Subtype Zaire, Strain Mayinga 1976) is a Rabbit Polyclonal antibody for the detection of Ebola Virus Glycoprotein Receptor-Binding Domain (EBOV GP RBD). The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-terminal sequences. Recently, great attention has been paid to GP for vaccines design and entry inhibitors isolation. GP is a class I fusion protein which assembles as trimers on viral surface and plays an important role in virus entry and attachment. Mature GP is a disulfide-linked heterodimer formed by two subunits, GP1 and GP2, which are generated from the proteolytical process of GP precursor (pre-GP) by cellular furin during virus assembly . The GP1 subunit contains a mucin domain and a receptor-binding domain (RBD); the GP2 subunit has a fusion peptide, a helical heptad-repeat (HR) region, a transmembrane (TM) domain, and a 4-residue cytoplasmic tail. The RBD of GP1 mediates the interaction of EBOV with cellular receptor (e.g. DC-SIGN/LSIGN, TIM-1, hMGL, NPC1, β-integrins, folate receptor-α, and Tyro3 family receptors), of which TIM1 and NPC1 are essential for EBOV entry; the mucin domain having N- and O-linked glycans enhances the viral attachment to cellular hMGL, and participates in shielding key neutralization epitopes, which helps the virus evades immune elimination. There are large conformation changes of GP2 during membrane fusion, which enhance the insertion of fusion loop into cellular membrane and facilitate the release of viral nucleocapsid core to cytoplasm.

Lassa Virus Pre-Glycoprotein Polyprotein GP Complex (LASV GPC) Antibody, Abbexa, abx377464

Lassa Virus Pre-Glycoprotein Polyprotein GP Complex (LASV GPC) Antibody is a Rabbit polyclonal antibody for the detection of Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Pre-Glycoprotein Polyprotein GP Complex (LASV GPC).