Search results for GSK3B

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx037712
Rabbit Polyclonal against the GSK3B protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx233674
GSK3B Antibody is a Rabbit Polyclonal against GSK3B.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC, IP
Conjugation
Unconjugated

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody, Abbexa, abx376354
Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody is a Rabbit Polyclonal antibody against Glycogen Synthase Kinase-3 Beta (GSK3B).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx233676
GSK3B Antibody is a Rabbit Polyclonal against GSK3B.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC, IP
Conjugation
Unconjugated

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody, Abbexa, abx033884
GSK3B, a member of the Ser/Thr protein kinase family, participates in the Wnt signaling pathway. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. GSK3B phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. The protein is inhibited when phosphorylated by AKT1 or ILK1. Expressed is detected in testis, thymus, prostate and ovary, and weakly in lung, brain and kidney.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody, Abbexa, abx455459
Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody is a Rabbit polyclonal antibody for the detection of Human Glycogen Synthase Kinase-3 Beta (GSK3B).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx233675
GSK3B Antibody is a Rabbit Polyclonal against GSK3B.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx329709
GSK3B Antibody is a Rabbit Polyclonal against GSK3B.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IP
Conjugation
Unconjugated

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx233673
GSK3B Antibody is a Rabbit Polyclonal against GSK3B.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx010856
Glycogen synthase kinase 3 (GSK-3), a serine-threonine kinase with two isoforms (alpha and beta), was originally discovered as a key enzyme in glycogen metabolism. GSK-3 was subsequently shown to function in cell division, proliferation, motility and survival. GSK-3 plays a role in a number of pathological conditions including cancer and diabetes and is increasingly seen as an important component of neurological diseases. GSK-3 phosphorylates tau and presenilin-1, which are involved in the development of Alzheimer's disease. Both isoforms of GSK-3 are ubiquitously expressed, although particularly high levels of GSK-3 beta are found in the brain where it is involved in synaptic plasticity, possibly via regulation of NMDA receptor trafficking. GSK-3 phosphorylates over 40 different substrates including signaling proteins, transcription factors and structural proteins, and is part of the signal transduction cascade of a large number of growth factors and cytokines. The activity of GSK is regulated by phosphorylation (Akt: Akt-mediated phosphorylation at Ser21 of GSK-3 alpha and Ser9 of GSK-3 beta, S6K, RSK, PKA and PKC), dephosphorylation (PP1 and PP2A), and by binding to protein complexes (with beta catenin, axin, CK1 and the APC complex).
Host
Mouse
Reactivity
Human, Mouse, Monkey, Rat
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
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