Search results for GSK3B

Showing 1 – 10 of107products
Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody Brand Logo
ID: BAB078786746

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx037712

Rabbit Polyclonal against the GSK3B protein.

Host

Rabbit

Reactivity

Human

Applications

ELISA, IHC

Conjugation

Unconjugated

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody Brand Logo
ID: BAB259235262

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx233674

GSK3B Antibody is a Rabbit Polyclonal against GSK3B.

Host

Rabbit

Reactivity

Human, Mouse, Rat

Applications

ELISA, WB, IHC, IF/ICC, IP

Conjugation

Unconjugated

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody Brand Logo
ID: BAB169011004

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody, Abbexa, abx376354

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody is a Rabbit Polyclonal antibody against Glycogen Synthase Kinase-3 Beta (GSK3B).

Host

Rabbit

Reactivity

Human

Applications

ELISA, WB, IHC, IF/ICC

Conjugation

Unconjugated

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody Brand Logo
ID: BAB546576123

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx233676

GSK3B Antibody is a Rabbit Polyclonal against GSK3B.

Host

Rabbit

Reactivity

Human, Mouse

Applications

ELISA, WB, IHC, IF/ICC, IP

Conjugation

Unconjugated

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody Brand Logo
ID: BAB024491671

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody, Abbexa, abx033884

GSK3B, a member of the Ser/Thr protein kinase family, participates in the Wnt signaling pathway. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. GSK3B phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. The protein is inhibited when phosphorylated by AKT1 or ILK1. Expressed is detected in testis, thymus, prostate and ovary, and weakly in lung, brain and kidney.

Host

Rabbit

Reactivity

Human

Applications

ELISA, WB, IHC

Conjugation

Unconjugated

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody Brand Logo
ID: BAB527008049

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody, Abbexa, abx455459

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody is a Rabbit polyclonal antibody for the detection of Human Glycogen Synthase Kinase-3 Beta (GSK3B).

Host

Rabbit

Reactivity

Human

Applications

ELISA, WB, IHC

Conjugation

Unconjugated

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody Brand Logo
ID: BAB382951941

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx233675

GSK3B Antibody is a Rabbit Polyclonal against GSK3B.

Host

Rabbit

Reactivity

Human, Mouse

Applications

ELISA, WB, IHC, IF/ICC, FCM

Conjugation

Unconjugated

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody Brand Logo
ID: BAB351655706

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx329709

GSK3B Antibody is a Rabbit Polyclonal against GSK3B.

Host

Rabbit

Reactivity

Human, Mouse, Rat

Applications

ELISA, WB, IHC, IP

Conjugation

Unconjugated

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody Brand Logo
ID: BAB463848265

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx233673

GSK3B Antibody is a Rabbit Polyclonal against GSK3B.

Host

Rabbit

Reactivity

Human, Mouse, Rat

Applications

ELISA, WB, IHC

Conjugation

Unconjugated

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody Brand Logo
ID: BAB687074858

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody, Abbexa, abx010856

Glycogen synthase kinase 3 (GSK-3), a serine-threonine kinase with two isoforms (alpha and beta), was originally discovered as a key enzyme in glycogen metabolism. GSK-3 was subsequently shown to function in cell division, proliferation, motility and survival. GSK-3 plays a role in a number of pathological conditions including cancer and diabetes and is increasingly seen as an important component of neurological diseases. GSK-3 phosphorylates tau and presenilin-1, which are involved in the development of Alzheimer's disease. Both isoforms of GSK-3 are ubiquitously expressed, although particularly high levels of GSK-3 beta are found in the brain where it is involved in synaptic plasticity, possibly via regulation of NMDA receptor trafficking. GSK-3 phosphorylates over 40 different substrates including signaling proteins, transcription factors and structural proteins, and is part of the signal transduction cascade of a large number of growth factors and cytokines. The activity of GSK is regulated by phosphorylation (Akt: Akt-mediated phosphorylation at Ser21 of GSK-3 alpha and Ser9 of GSK-3 beta, S6K, RSK, PKA and PKC), dephosphorylation (PP1 and PP2A), and by binding to protein complexes (with beta catenin, axin, CK1 and the APC complex).

Host

Mouse

Reactivity

Human, Mouse, Monkey, Rat

Applications

ELISA, WB, IHC, IF/ICC, FCM

Conjugation

Unconjugated

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