Search results for db

Anti-Triplex DNA Antibody (Jel318), AntibodySystem, RGK24602

Anti-Human TARDBP/TDP43 Antibody (3H), AntibodySystem, RHG42201

Cofilin (pS3) Antibody, Abbexa, abx032106

Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

CDK2 (pT14) Antibody, Abbexa, abx032049

CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation.

Bcl2-Associated Agonist of Cell Death Phospho-Thr94 (BAD pT94) Antibody, Abbexa, abx032137

Promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

Microtubule-Associated Protein Tau (MAPT) Antibody (PerCP), Abbexa, abx450175

Microtubule-Associated Protein Tau (MAPT) Antibody (PerCP) is a Mouse Monoclonal against Microtubule-Associated Protein Tau (MAPT).

TSC1 (pY297) Antibody, Abbexa, abx032284

This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.

PTEN (pS229) Antibody, Abbexa, abx032189

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3, 4, 5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.

Amyloid Fibrils (OC) Antibody (PerCP), Abbexa, abx448399

Amyloid Fibrils (OC) Antibody (PerCP) is a Rabbit Polyclonal against Amyloid.

Mouse TSC1 (pS321) Antibody, Abbexa, abx032221

In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).