Search results for oncogene homolog

V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ERBB3) Antibody, Abbexa, abx430340
ERBB3 Antibody is a Goat Polyclonal antibody against ERBB3.
Host
Goat
Reactivity
Human
Applications
P-ELISA, IHC, IF/ICC, FCM
Conjugation
Unconjugated

V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ERBB3) Antibody, Abbexa, abx116601
V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) Antibody is a Rabbit Polyclonal antibody against V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated

V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ERBB3) Antibody, Abbexa, abx000910
ERBB3 Antibody is a Rabbit Polyclonal antibody against ERBB3. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated

V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN) Antibody, Abbexa, abx033639
Lyn is a protein tyrosine kinase which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated

V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN) Antibody, Abbexa, abx011096
Lyn (also known as p53/56 Lyn) is a membrane-associated protein tyrosine kinase (PTK) mostly expressed in hemopoietic cells which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis. A member of the Src family of PTKs, there are two known isoforms for Lyn which plays an indispensable role in the Fc epsilon RI (Fcer1) and the B-cell IgM receptor signaling pathway and is essential for Syk activation and Lat phosphorylation after Fcer1 aggregation and can also phosphor-ylate Tec on multiple residues. Lyn can also be regulated by IL-2 and IL-3.Lyn is a member of the src family of non-receptor protein tyrosine kinases that is predominantly expressed in haematopoietic tissues. Like all members of the src family, lyn is thought to participate in signal transduction from cell surface receptors that lack intrinsic tyrosine kinase activity. It is associated with a number of cell surface receptors including the B cell antigen receptor and immunoglobulin E receptor (FceRI).
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated

V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (Lyn) Antibody, Abbexa, abx139721
Lyn Antibody is a Mouse Monoclonal against Lyn.
Host
Mouse
Reactivity
Human, Mouse, Rat
Applications
WB, IF/ICC, IP
Conjugation
Unconjugated

V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN) Antibody, Abbexa, abx234904
LYN Antibody is a Mouse Monoclonal against LYN.
Host
Mouse
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated

V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ERBB3) Antibody, Abbexa, abx214446
ERBB3 Antibody is a Rabbit Polyclonal against ERBB3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated

V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ERBB3) Antibody, Abbexa, abx329586
ERBB3 Antibody is a Rabbit Polyclonal against ERBB3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated

V-Erb A Erythroblastic Leukemia Viral Oncogene Homolog 4 (ErbB4) Antibody (PE), Abbexa, abx270950
V-Erb A Erythroblastic Leukemia Viral Oncogene Homolog 4 (ErbB4) Antibody (PE) is a Rabbit Polyclonal Antibody conjugated to PE against V-Erb A Erythroblastic Leukemia Viral Oncogene Homolog 4 (ErbB4) for use in flow cytometry.
Host
Rabbit
Reactivity
Human
Applications
FCM
Conjugation
PE
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