Search results for Fmr1 antibody

Fmr1 antibody, Genetex, GTX125996

FMR1 antibody, Covalab, Ref 00021038

FMR1 antibody (1D10), Covalab, Ref 00110408

Anti-FMR1 Antibody (R2C95), AntibodySystem, RHG10301

Anti-FMR1 Antibody (R3R41), AntibodySystem, RHG10304

Anti-Drosophila FMR1 antibody [6A15], Abcam, AB10299

Fragile X syndrome is the most common inherited form of mental retardation. It is caused by loss of FMR1 gene activity due to either lack of expression or expression of a mutant form of the protein. In mammals, FMR1 is a member of a small protein family that consists of FMR1, FXR1, and FXR2. All three members bind RNA and contain sequence motifs that are commonly found in RNA-binding proteins, including two KH domains and an RGG box.The Drosophila genome contains a single gene homologous to the FXR family. dFMR1 is subjected to transcriptional and posttranscriptional regulation during development and it homomerizes, like its human counterpart. dFMR1 profile of expression recapitulates that of the human FXR protein family: it is highly enriched in muscles, in central nervous system and in gonads. In the larval brain, anti-dFMR1 also recognizes mushroom bodies, a centre that mediates learning and memory. These features make the fly an ideal system to analyse the role of the FXR family and to identify genes in the FMRP pathway.

Fragile X Mental Retardation 1 (FMR1) Antibody, Abbexa, abx004316

FMR1 Antibody is a Rabbit Polyclonal antibody against FMR1. The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Fragile X Mental Retardation 1 (FMR1) Antibody, Abbexa, abx431828

FMR1 Antibody is a Goat Polyclonal antibody against FMR1.

Fragile X Mental Retardation 1 (FMR1) Antibody, Abbexa, abx172471

This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Fragile X Mental Retardation 1 (FMR1) Antibody is a Mouse Monoclonal antibody against Fragile X Mental Retardation 1 (FMR1).

Fragile X Mental Retardation 1 (FMR1) Antibody, Abbexa, abx010789

FMR1, also known as POF, FMRP, FRAXA. Entrez Protein: NP002015. It is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.