Search results for beta 3

Gap Junction Beta-3 Protein / CX31 (GJB3) Antibody, Abbexa, abx028498

Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variabilis (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.

Gap Junction Beta-3 Protein / CX31 (GJB3) Antibody, Abbexa, abx339928

Gap Junction Beta-3 Protein / CX31 (GJB3) Antibody is a Rabbit Polyclonal against Gap Junction Beta-3 Protein / CX31 (GJB3).

Integrin beta 3 antibody [3C12-G2-E4-H9], Genetex, GTX49161

Alpha-V/Beta-3 Integrin, Human, mAb BV3, Hycult Biotech, HM2034

The monoclonal antibody BV3 recognizes human alpha-V/beta-3 integrin present on human cells. Integrins are a superfamily of αβ heterodimeric cell-surface adhesion receptors found in many species. They are  expressed on a variety of cells and mediate numerous physiological processes, including inflammation, migration, adhesion and proliferation. The β3 family consist of 2 members: αIIbβ3 and αvβ3, which mediate cell-cell and cell-ECM interactions and are important for cellularc migration, regulation of gene expression, cell survival, adhesion and differentiation. All processes which are involved in tissue development, angiogenesis and thrombosis. Each subunit consist of an extracellular domain, a single transmembrane segment and a cytoplasmic tail. They connect to the actin cytoskeleton via adaptor proteins that bind theircytoplasmic tails. Cell matrix adhesions also act as signaling units by their capacity to organize the actin cytoskeleton and to accumulate various signaling intermediates. Integrin αvβ3 was originally identified as the vitronectin receptor. Nevertheless, other ligands include fibrinogen, fibronectin, laminin, thrombospondin, Von Willebrand factor, tenascin, osteopontin and several forms of collagen. The interactions of integrin αvβ3 to those ligands is mediated by the RGD (Arg-Gly-Asp) sequence motif present in these proteins. Deregulation of β3 integrins is involved in e.g. autoimmune diseases, cardiovascular disorders, transplant rejection and tumorigenesis. In contribution to the latter, integrin αvβ3 contribute by supporting growth of small (tumor) blood vessels thereby potentiating the metastatic potential. Overexpression of integrin αvβ3 has been demonstrated in various tumors and activated endothelium.

Human Beta-3 adrenergic receptor (ADRB3) ELISA Kit, Abbkine, KTE60951

• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.

Integrin Alpha IIb / Beta 3 (ITGA2B/3) Antibody, Abbexa, abx421373

Integrin Alpha IIb / Beta 3 (ITGA2B/3) Antibody is a Human Monoclonal antibody for the detection of Integrin Alpha IIb / Beta 3 (ITGA2B/3) in Human samples.

Phospholipase C Beta 3, Phosphoinositide Specific (PLCB3) Antibody, Abbexa, abx328749

PLCB3 Antibody is a Rabbit Polyclonal against PLCB3.

Cholinergic Receptor, Nicotinic, Beta 3 (CHRNB3) Antibody (HRP), Abbexa, abx336775

CHRNB3 Antibody (HRP) is a Rabbit Polyclonal against CHRNB3.

TGF beta 1/TGF beta 3 Antibody (YA6164), MedChemexpress, HY-P86472

TGF beta 1/TGF beta 3 Antibody (YA6164) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TGF beta 1/TGF beta 3.

Anti-Integrin alpha 2b + beta 3 antibody [P256], Abcam, AB11027