Search results for Alpha-synuclein

Alpha-synuclein Truncation 1-122 mAb [MJFF-D-10B7], ABclonal, A27452

Biotin anti-alpha-Synuclein, aggregated Antibody, α-Synuclein, A17183A, BioLegend, 864905

Biotin anti-alpha-Synuclein, aggregated Antibody, α-Synuclein, A17183A, BioLegend, 864906

[KO Validated] N-terminal alpha-synuclein mAb [MJFF-B-3A4], ABclonal, A27117

Anti-Alpha-synuclein antibody [EPR23675-102] - BSA and Azide free (Capture), Abcam, AB281203

ab281203 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Mouse SNCA. The recommended pair for sandwich ELISA is: Capture: ab281203, Mouse SNCA Capture Antibody (unconjugated) Detector: ab281053 , Mouse SNCA Detector Antibody (unconjugated) The reference range value is 78 - 5000 pg/mL. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Sandwich ELISA The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

Anti-Alpha-synuclein antibody [EPR23675-54] - BSA and Azide free (Detector), Abcam, AB281053

ab281053 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Mouse SNCA. The recommended pair for sandwich ELISA is: Capture: ab281203 , Mouse SNCA Capture Antibody (unconjugated) Detector: ab281053, Mouse SNCA Detector Antibody (unconjugated) The reference range value is 78 - 5000 pg/ml. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Sandwich ELISA The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

Anti-Alpha-synuclein antibody [MJFR1] - BSA and Azide free (Capture/Detector), Abcam, AB259612

What is this antibody validated in? Anti-Alpha-synuclein antibody [MJFR1] - BSA and Azide free (Capture/Detector) (ab259612) is a rabbit recombinant monoclonal antibody and is validated for use in ELISA in Human samples. Other related products We have a range of other formats of antibody clone [MJFR1] also available for your convenience: ab138501 , Carrier free - ab209420 , Carrier free - ab259612, ab309157 , Carrier free - ab309158 , Biotin - ab309388 , HRP - ab314243 , ab320839 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Sandwich ELISA The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

Anti-Alpha-synuclein (phospho S129) antibody [EP1536Y] - BSA and Azide free, Abcam, AB209422

What is this antibody validated in? Anti-Alpha-synuclein (phospho S129) antibody [EP1536Y] - BSA and Azide free (ab209422) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr), ELISA, Dot Blot in Human, Mouse, Rat samples. What is the molecular weight of Alpha-synuclein? Anti-Alpha-synuclein (phospho S129) [EP1536Y] - BSA and Azide free (ab209422) specifically detects a band for Alpha-synuclein (UniProt: P37840) at a molecular weight of 14kDa. Trusted by the scientific community Anti-Alpha-synuclein (phospho S129) [EP1536Y] - BSA and Azide free (ab209422) was first used in a scientific publication in 2016 and has been cited over 20 times in peer-reviewed journals. Other related products We have a range of other formats of antibody clone [EP1536Y] also available for your convenience: ab51253 , Carrier free - ab209422, Alexa Fluor® 594 - ab282652 , Alexa Fluor® 568 - ab307166 , Alexa Fluor® 488 - ab310949 , Alexa Fluor® 647 - ab311067 , Alexa Fluor® 555 - ab313137 , Alexa Fluor® 750 - ab321645 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Species reactivity Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information. Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.

Anti-Alpha-synuclein (phospho S129) antibody [MJF-R13 (8-8)], Abcam, AB168381

Anti-Alpha-synuclein (phospho S129) antibody [MJF-R13 (8-8)] (ab168381) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in IHC-P, WB in human samples. Anti-Alpha-synuclein (phospho S129) antibody [MJF-R13 (8-8)] (ab168381) has been cited over 40 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Alpha-synuclein (phospho S129) antibody (Anti-pS129 alpha-synuclein antibody) [MJF-R13 (8-8)] (ab168381) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Alpha-synuclein (phospho S129) antibody [MJF-R13 (8-8)] (ab168381) has 4 independent reviews from customers. Anti-Alpha-synuclein (phospho S129) antibody [MJF-R13 (8-8)] (ab168381) specifically detects Alpha-synuclein Phospho-S129 (UniProt ID: P37840; Molecular weight: 14kDa) and is sold in 100 µL and 1 mL selling sizes. Anti-Alpha-synuclein (phospho S129) antibody [MJF-R13 (8-8)] (ab168381) was developed by Abcam in partnership with the Michael J. Fox Foundation for Parkinson's Research. Alpha-synuclein phosphorylated at serine 129 (pS129; SNCA/NACP) is a key pathological marker in neurodegenerative diseases such as Parkinson's disease. This phosphorylation event is associated with the abnormal aggregation of alpha-synuclein into Lewy bodies, which are indicative of disease. Studies have shown that pS129 not only promotes the aggregation of alpha-synuclein but also increases its neurotoxicity, contributing to neuronal death and disease progression Alpha-synuclein was the first gene to be linked to Parkinson's disease (PD) and remains the most promising link to PD pathogenesis, where there is genetic evidence that it may play a causal role. In the brain, alpha-synuclein is concentrated in presynaptic nerve terminals. The deposition of the abundant presynaptic brain protein alpha-synuclein as fibrillary aggregates in neurons or glial cells is a hallmark lesion in a subset of neurodegenerative disorders. These disorders include Parkinson's disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy, collectively referred to as synucleinopathies. Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive accumulation in selected neurons of protein inclusions containing alpha-synuclein and ubiquitin. Recent studies also indicate that alpha-synuclein undergoes post-translational modification. Though the role of many of these modifications is still under investigation, phosphorylation at Serine 129 may affect alpha-synuclein aggregations and may also serve as marker of disease pathogenesis. With the advent of this phospho-specific Serine 129 antibody, The Michael J. Fox Foundation hopes to ensure that the putative role of this modification can be further examined by all researchers. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Collaborations This antibody was developed with support from The Michael J. Fox Foundation.

HRP anti-alpha-Synuclein, 34-45 Antibody anti-Synuclein - A15110D, BioLegend, 849104

By ELISA, this antibody cross-reacts with ß-synuclein.